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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABL1 All Species: 27.58
Human Site: T751 Identified Species: 55.15
UniProt: P00519 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00519 NP_005148.2 1130 122873 T751 G R Q F D S S T F G G H K S E
Chimpanzee Pan troglodytes XP_520319 1140 124124 T761 G R Q F D S S T F G G H K S E
Rhesus Macaque Macaca mulatta XP_001118598 973 105035 V618 G E N R S D Q V A R G T V T P
Dog Lupus familis XP_548413 1131 122978 T751 G R Q F D S S T F G G H K S E
Cat Felis silvestris
Mouse Mus musculus P00520 1123 122654 T750 G K Q F D S S T F G G H K S E
Rat Rattus norvegicus XP_231137 1124 122522 T750 G K Q F D S S T F G G H K S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507150 1174 128492 F793 R Q F D S S T F A G H K S E K
Chicken Gallus gallus XP_415463 1125 123043 T749 G R Q F D S S T F G G H K S E
Frog Xenopus laevis NP_001084399 1102 120702 E746 S G K S G S S E E Q P K P F P
Zebra Danio Brachydanio rerio XP_001337899 1060 117143 S704 F L R S S S S S S M P P G S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P00522 1620 171570 T1218 K L T N G N S T G S G F K A Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P03949 1224 138308 S859 V P P S R N A S V S V R P D S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 78.7 91.5 N.A. 87.6 87.6 N.A. 81.6 83.6 54.2 69.9 N.A. 36.1 N.A. 33.1 N.A.
Protein Similarity: 100 97.7 81.1 93.8 N.A. 91.1 90.9 N.A. 86.2 88.4 65.4 77.2 N.A. 47 N.A. 48.9 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 13.3 100 13.3 20 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 33.3 100 20 40 N.A. 46.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 17 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 50 9 0 0 0 0 0 0 0 9 9 % D
% Glu: 0 9 0 0 0 0 0 9 9 0 0 0 0 9 50 % E
% Phe: 9 0 9 50 0 0 0 9 50 0 0 9 0 9 0 % F
% Gly: 59 9 0 0 17 0 0 0 9 59 67 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 50 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 17 9 0 0 0 0 0 0 0 0 17 59 0 9 % K
% Leu: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 17 9 17 0 17 % P
% Gln: 0 9 50 0 0 0 9 0 0 9 0 0 0 0 9 % Q
% Arg: 9 34 9 9 9 0 0 0 0 9 0 9 0 0 0 % R
% Ser: 9 0 0 25 25 75 75 17 9 17 0 0 9 59 9 % S
% Thr: 0 0 9 0 0 0 9 59 0 0 0 9 0 9 0 % T
% Val: 9 0 0 0 0 0 0 9 9 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _