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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABL1
All Species:
36.36
Human Site:
Y185
Identified Species:
72.73
UniProt:
P00519
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00519
NP_005148.2
1130
122873
Y185
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Chimpanzee
Pan troglodytes
XP_520319
1140
124124
Y195
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Rhesus Macaque
Macaca mulatta
XP_001118598
973
105035
R106
R
R
M
V
T
G
R
R
P
G
P
H
T
A
G
Dog
Lupus familis
XP_548413
1131
122978
Y185
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Cat
Felis silvestris
Mouse
Mus musculus
P00520
1123
122654
Y185
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Rat
Rattus norvegicus
XP_231137
1124
122522
Y185
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507150
1174
128492
Y229
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Chicken
Gallus gallus
XP_415463
1125
123043
Y185
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Frog
Xenopus laevis
NP_001084399
1102
120702
Y220
T
A
S
D
G
K
V
Y
V
T
A
E
S
R
F
Zebra Danio
Brachydanio rerio
XP_001337899
1060
117143
Y180
T
A
S
D
G
K
L
Y
V
S
S
E
S
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P00522
1620
171570
F312
E
D
P
D
G
K
V
F
V
T
Q
E
A
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P03949
1224
138308
F252
V
D
N
T
E
K
M
F
I
T
Q
E
V
K
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
78.7
91.5
N.A.
87.6
87.6
N.A.
81.6
83.6
54.2
69.9
N.A.
36.1
N.A.
33.1
N.A.
Protein Similarity:
100
97.7
81.1
93.8
N.A.
91.1
90.9
N.A.
86.2
88.4
65.4
77.2
N.A.
47
N.A.
48.9
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
80
100
N.A.
40
N.A.
20
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
0
0
0
0
0
0
0
0
9
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
84
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
9
0
0
0
0
0
0
92
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
92
% F
% Gly:
0
0
0
0
84
9
0
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
92
0
0
0
0
0
0
0
17
0
% K
% Leu:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
9
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
9
9
0
0
0
0
9
9
0
0
0
0
0
75
0
% R
% Ser:
0
0
75
0
0
0
0
0
0
67
67
0
75
0
0
% S
% Thr:
75
0
0
9
9
0
0
0
0
25
0
0
9
0
0
% T
% Val:
9
0
0
9
0
0
17
0
84
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _