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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOS
All Species:
13.64
Human Site:
S218
Identified Species:
25
UniProt:
P00540
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00540
NP_005363.1
346
37820
S218
E
Q
D
V
C
K
I
S
D
F
G
C
S
E
K
Chimpanzee
Pan troglodytes
XP_528144
346
37828
S218
E
Q
D
V
C
K
I
S
D
F
G
C
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001087400
305
33010
G180
V
C
K
I
S
D
F
G
C
S
E
K
L
E
D
Dog
Lupus familis
XP_544088
372
41133
G244
E
Q
D
V
C
K
I
G
D
F
G
C
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P00536
390
42872
S262
E
Q
D
V
C
K
I
S
D
F
G
C
S
Q
K
Rat
Rattus norvegicus
P00539
339
37603
S213
E
K
D
V
C
K
I
S
D
F
G
C
S
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10741
349
38245
G222
E
H
G
A
C
K
I
G
D
F
G
C
S
Q
R
Frog
Xenopus laevis
P12965
359
39143
Q212
I
G
D
F
G
C
S
Q
R
L
R
E
G
D
E
Zebra Danio
Brachydanio rerio
NP_991143
329
36509
I204
S
E
Q
G
V
C
K
I
A
D
F
G
C
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1Y5
476
53320
I317
S
D
K
A
E
R
C
I
L
K
L
T
D
F
G
Sea Urchin
Strong. purpuratus
XP_789415
418
47752
C285
D
Y
D
V
C
R
L
C
D
Y
G
C
S
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130627
368
40934
A208
E
D
M
S
V
K
V
A
D
F
G
I
S
C
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2MHE4
390
44263
A229
D
E
M
R
V
K
V
A
D
F
G
T
S
C
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
78.4
N.A.
65.3
71
N.A.
N.A.
62.1
53.7
46.5
N.A.
N.A.
N.A.
20.1
26.3
Protein Similarity:
100
99.4
86.4
83.5
N.A.
71.7
78.9
N.A.
N.A.
72.7
66.5
62.1
N.A.
N.A.
N.A.
36.1
40.6
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
86.6
N.A.
N.A.
60
6.6
0
N.A.
N.A.
N.A.
0
46.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
N.A.
73.3
20
6.6
N.A.
N.A.
N.A.
6.6
86.6
Percent
Protein Identity:
N.A.
29.6
N.A.
22.8
N.A.
N.A.
Protein Similarity:
N.A.
43.2
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
16
8
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
54
16
8
8
8
0
0
54
8
16
0
% C
% Asp:
16
16
54
0
0
8
0
0
70
8
0
0
8
8
8
% D
% Glu:
54
16
0
0
8
0
0
0
0
0
8
8
0
31
8
% E
% Phe:
0
0
0
8
0
0
8
0
0
62
8
0
0
8
8
% F
% Gly:
0
8
8
8
8
0
0
24
0
0
70
8
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
47
16
0
0
0
8
0
0
0
% I
% Lys:
0
8
16
0
0
62
8
0
0
8
0
8
0
0
39
% K
% Leu:
0
0
0
0
0
0
8
0
8
8
8
0
8
0
16
% L
% Met:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
31
8
0
0
0
0
8
0
0
0
0
0
31
8
% Q
% Arg:
0
0
0
8
0
16
0
0
8
0
8
0
0
0
8
% R
% Ser:
16
0
0
8
8
0
8
31
0
8
0
0
70
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% T
% Val:
8
0
0
47
24
0
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _