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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOS
All Species:
19.09
Human Site:
S280
Identified Species:
35
UniProt:
P00540
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00540
NP_005363.1
346
37820
S280
T
T
K
Q
A
P
Y
S
G
E
R
Q
H
I
L
Chimpanzee
Pan troglodytes
XP_528144
346
37828
S280
T
T
K
Q
A
P
Y
S
G
E
R
Q
H
I
L
Rhesus Macaque
Macaca mulatta
XP_001087400
305
33010
R242
Q
A
P
Y
S
G
E
R
Q
H
I
L
Y
A
V
Dog
Lupus familis
XP_544088
372
41133
S306
A
T
K
E
A
P
Y
S
G
E
R
Q
Y
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P00536
390
42872
S324
T
T
R
E
V
P
Y
S
G
E
P
Q
Y
V
Q
Rat
Rattus norvegicus
P00539
339
37603
G275
T
R
E
V
P
Y
S
G
E
P
Q
Y
V
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10741
349
38245
L284
V
M
R
E
Q
P
Y
L
G
E
R
Q
Y
V
L
Frog
Xenopus laevis
P12965
359
39143
T274
V
S
R
E
L
P
Y
T
G
D
R
Q
C
V
L
Zebra Danio
Brachydanio rerio
NP_991143
329
36509
Y266
L
L
T
R
E
P
P
Y
E
G
D
R
Q
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1Y5
476
53320
S379
F
S
G
Y
P
P
F
S
E
E
Y
T
D
M
T
Sea Urchin
Strong. purpuratus
XP_789415
418
47752
E347
L
W
Q
M
L
T
R
E
T
P
Y
A
G
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130627
368
40934
P270
V
P
F
S
D
M
T
P
E
Q
A
A
V
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2MHE4
390
44263
P291
L
P
F
Q
G
M
T
P
V
Q
A
A
F
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
78.4
N.A.
65.3
71
N.A.
N.A.
62.1
53.7
46.5
N.A.
N.A.
N.A.
20.1
26.3
Protein Similarity:
100
99.4
86.4
83.5
N.A.
71.7
78.9
N.A.
N.A.
72.7
66.5
62.1
N.A.
N.A.
N.A.
36.1
40.6
P-Site Identity:
100
100
0
73.3
N.A.
53.3
6.6
N.A.
N.A.
46.6
40
6.6
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
100
20
93.3
N.A.
80
20
N.A.
N.A.
73.3
80
26.6
N.A.
N.A.
N.A.
40
6.6
Percent
Protein Identity:
N.A.
29.6
N.A.
22.8
N.A.
N.A.
Protein Similarity:
N.A.
43.2
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
24
0
0
0
0
0
16
24
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
8
0
8
0
0
% D
% Glu:
0
0
8
31
8
0
8
8
31
47
0
0
0
8
0
% E
% Phe:
8
0
16
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
8
0
8
8
0
8
47
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
8
% I
% Lys:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
24
8
0
0
16
0
0
8
0
0
0
8
0
0
39
% L
% Met:
0
8
0
8
0
16
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
16
8
0
16
62
8
16
0
16
8
0
0
0
0
% P
% Gln:
8
0
8
24
8
0
0
0
8
16
8
47
8
8
8
% Q
% Arg:
0
8
24
8
0
0
8
8
0
0
39
8
0
0
0
% R
% Ser:
0
16
0
8
8
0
8
39
0
0
0
0
0
0
0
% S
% Thr:
31
31
8
0
0
8
16
8
8
0
0
8
0
0
8
% T
% Val:
24
0
0
8
8
0
0
0
8
0
0
0
16
31
24
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
8
47
8
0
0
16
8
31
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _