KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOS
All Species:
25.76
Human Site:
Y75
Identified Species:
47.22
UniProt:
P00540
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00540
NP_005363.1
346
37820
Y75
A
G
G
F
G
S
V
Y
K
A
T
Y
R
G
V
Chimpanzee
Pan troglodytes
XP_528144
346
37828
Y75
A
G
G
F
G
S
V
Y
K
A
T
Y
R
G
V
Rhesus Macaque
Macaca mulatta
XP_001087400
305
33010
L46
T
P
P
R
A
P
R
L
P
R
R
L
A
W
C
Dog
Lupus familis
XP_544088
372
41133
Y102
A
G
G
F
G
S
V
Y
K
A
T
Y
H
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P00536
390
42872
Y125
S
G
G
F
G
S
V
Y
K
A
T
Y
H
G
V
Rat
Rattus norvegicus
P00539
339
37603
Y76
S
G
G
F
G
S
V
Y
K
A
T
Y
H
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10741
349
38245
Y79
S
G
G
F
G
A
V
Y
K
A
T
Y
H
G
V
Frog
Xenopus laevis
P12965
359
39143
Y78
S
G
G
F
G
S
V
Y
R
A
T
Y
R
G
E
Zebra Danio
Brachydanio rerio
NP_991143
329
36509
G70
L
E
P
I
G
S
G
G
F
G
T
V
F
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1Y5
476
53320
V122
H
S
R
N
G
T
L
V
N
Q
E
M
I
G
K
Sea Urchin
Strong. purpuratus
XP_789415
418
47752
K92
L
Q
S
A
F
I
L
K
G
D
T
E
F
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130627
368
40934
F71
K
L
E
I
R
G
K
F
A
S
G
R
H
S
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2MHE4
390
44263
W79
S
K
G
E
R
E
E
W
T
A
D
L
S
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
78.4
N.A.
65.3
71
N.A.
N.A.
62.1
53.7
46.5
N.A.
N.A.
N.A.
20.1
26.3
Protein Similarity:
100
99.4
86.4
83.5
N.A.
71.7
78.9
N.A.
N.A.
72.7
66.5
62.1
N.A.
N.A.
N.A.
36.1
40.6
P-Site Identity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
80
20
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
20
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
29.6
N.A.
22.8
N.A.
N.A.
Protein Similarity:
N.A.
43.2
N.A.
42
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
8
8
8
0
0
8
62
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
8
8
8
0
8
8
0
0
0
8
8
0
0
8
% E
% Phe:
0
0
0
54
8
0
0
8
8
0
0
0
16
0
0
% F
% Gly:
0
54
62
0
70
8
8
8
8
8
8
0
0
62
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% H
% Ile:
0
0
0
16
0
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
8
0
0
0
0
8
8
47
0
0
0
0
0
8
% K
% Leu:
16
8
0
0
0
0
16
8
0
0
0
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
16
0
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
0
0
0
16
0
% Q
% Arg:
0
0
8
8
16
0
8
0
8
8
8
8
24
8
8
% R
% Ser:
39
8
8
0
0
54
0
0
0
8
0
0
8
8
0
% S
% Thr:
8
0
0
0
0
8
0
0
8
0
70
0
0
0
0
% T
% Val:
0
0
0
0
0
0
54
8
0
0
0
8
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _