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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGK1
All Species:
52.77
Human Site:
S415
Identified Species:
82.92
UniProt:
P00558
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00558
NP_000282.1
417
44615
S415
L
P
G
V
D
A
L
S
N
I
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_518531
417
44783
S415
L
P
G
V
E
A
L
S
N
I
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001100787
417
44568
S415
L
P
G
V
D
A
L
S
N
I
_
_
_
_
_
Dog
Lupus familis
XP_849992
417
44444
S415
L
P
G
V
D
A
L
S
S
V
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P09411
417
44532
S415
L
P
G
V
D
A
L
S
N
V
_
_
_
_
_
Rat
Rattus norvegicus
P16617
417
44520
S415
L
P
G
V
D
A
L
S
N
V
_
_
_
_
_
Wallaby
Macropus eugenll
P29408
417
44960
N415
L
P
G
V
S
T
L
N
N
V
_
_
_
_
_
Platypus
Ornith. anatinus
XP_001507304
570
61329
S568
L
P
G
V
A
A
L
S
S
V
_
_
_
_
_
Chicken
Gallus gallus
P51903
417
44698
S415
L
P
G
V
D
A
L
S
S
V
_
_
_
_
_
Frog
Xenopus laevis
NP_001086928
417
44564
S415
L
P
G
V
D
A
L
S
N
V
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_998552
417
44672
S415
L
P
G
V
D
A
L
S
N
V
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01604
415
43843
T413
L
P
G
V
A
A
L
T
S
A
_
_
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91427
417
44094
S414
L
P
G
V
D
A
L
S
P
A
Q
_
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00560
416
44720
S413
L
P
G
V
A
F
L
S
E
K
K
_
_
_
_
Red Bread Mold
Neurospora crassa
P38667
418
45038
S415
L
P
G
V
V
A
L
S
E
R
Q
_
_
_
_
Conservation
Percent
Protein Identity:
100
87.2
99.7
96.4
N.A.
97.8
97.3
91.1
63.5
88.4
85.6
88.2
N.A.
70
N.A.
72.4
N.A.
Protein Similarity:
100
94.7
100
98.8
N.A.
99
98.8
95.6
70.3
96.1
94.2
93
N.A.
82
N.A.
83.6
N.A.
P-Site Identity:
100
90
100
80
N.A.
90
90
60
70
80
90
90
N.A.
60
N.A.
72.7
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
80
90
100
100
100
N.A.
80
N.A.
72.7
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
65.2
68.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
76.9
80.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
54.5
63.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
63.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
87
0
0
0
14
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% K
% Leu:
100
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
54
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
0
0
87
27
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
100
7
0
0
0
0
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
80
100
100
100
100
% _