Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGK1 All Species: 41.82
Human Site: S77 Identified Species: 65.71
UniProt: P00558 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00558 NP_000282.1 417 44615 S77 V P M P D K Y S L E P V A V E
Chimpanzee Pan troglodytes XP_518531 417 44783 S77 V P M P D K Y S L A P V A V E
Rhesus Macaque Macaca mulatta XP_001100787 417 44568 S77 V P M P D K Y S L E P V A V E
Dog Lupus familis XP_849992 417 44444 S77 V P M P D K Y S L G P V A V E
Cat Felis silvestris
Mouse Mus musculus P09411 417 44532 S77 V P M P D K Y S L E P V A A E
Rat Rattus norvegicus P16617 417 44520 S77 V P M P D K Y S L E P V A A E
Wallaby Macropus eugenll P29408 417 44960 S77 V P M P D K Y S L E P V A A E
Platypus Ornith. anatinus XP_001507304 570 61329 S230 V P M P D K Y S L G P V A V E
Chicken Gallus gallus P51903 417 44698 S77 V P M P D K F S F S P V A V E
Frog Xenopus laevis NP_001086928 417 44564 S77 V P M P D K Y S L A P A A E E
Zebra Danio Brachydanio rerio NP_998552 417 44672 S77 V P M P D K Y S L E P V A A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01604 415 43843 L76 N K N I K Y T L A P V A A E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91427 417 44094 L77 R R Q D K Y T L K P V A E E L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00560 416 44720 L77 E R N E K Y S L A P V A K E L
Red Bread Mold Neurospora crassa P38667 418 45038 L78 K P N P K Y S L K P V V P E L
Conservation
Percent
Protein Identity: 100 87.2 99.7 96.4 N.A. 97.8 97.3 91.1 63.5 88.4 85.6 88.2 N.A. 70 N.A. 72.4 N.A.
Protein Similarity: 100 94.7 100 98.8 N.A. 99 98.8 95.6 70.3 96.1 94.2 93 N.A. 82 N.A. 83.6 N.A.
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 93.3 93.3 93.3 80 80 93.3 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 93.3 100 93.3 N.A. 93.3 93.3 93.3 93.3 86.6 80 93.3 N.A. 6.6 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 65.2 68.6
Protein Similarity: N.A. N.A. N.A. N.A. 76.9 80.3
P-Site Identity: N.A. N.A. N.A. N.A. 0 20
P-Site Similarity: N.A. N.A. N.A. N.A. 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 14 14 0 27 80 27 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 74 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 0 0 7 0 0 0 0 0 40 0 0 7 34 74 % E
% Phe: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 7 0 0 27 74 0 0 14 0 0 0 7 0 0 % K
% Leu: 0 0 0 0 0 0 0 27 67 0 0 0 0 0 27 % L
% Met: 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 80 0 80 0 0 0 0 0 27 74 0 7 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 14 74 0 7 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % T
% Val: 74 0 0 0 0 0 0 0 0 0 27 74 0 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 27 67 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _