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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK1 All Species: 30.61
Human Site: S51 Identified Species: 56.11
UniProt: P00568 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00568 NP_000467.1 194 21635 S51 R S E V S S G S A R G K K L S
Chimpanzee Pan troglodytes XP_520278 232 25886 S89 R S E V S S G S A R G K K L S
Rhesus Macaque Macaca mulatta XP_001094708 194 21601 S51 R A E V S S G S A R G K K L S
Dog Lupus familis XP_547325 561 63083 S419 R N E L S S E S E R S K L I R
Cat Felis silvestris
Mouse Mus musculus Q9R0Y5 194 21521 S51 R A E V S S G S E R G K K L S
Rat Rattus norvegicus P39069 194 21565 S51 R A E V S S G S S R G K M L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P05081 194 21665 S52 R A E V S S G S E R G K K L Q
Frog Xenopus laevis Q7ZX23 193 22088 E51 K P D S Q Y G E L I E S Y I R
Zebra Danio Brachydanio rerio Q7ZWE9 196 22405 Q51 R T D S E F G Q L I D S Y I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20140 210 22579 S63 R D E V K S G S P R G A Q L T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P43188 222 24849 K52 A A G S E N G K R A K E F M E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04905 202 22463 S57 R A E I K S G S E N G T M I Q
Baker's Yeast Sacchar. cerevisiae P15700 204 22915 G59 R A E Q G R A G S Q Y G E L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.1 98.9 20.3 N.A. 88.6 90.2 N.A. N.A. 83.5 45.8 41.8 N.A. N.A. N.A. 55.2 N.A.
Protein Similarity: 100 82.3 100 28.3 N.A. 96.9 97.4 N.A. N.A. 91.2 68 65.3 N.A. N.A. N.A. 70.4 N.A.
P-Site Identity: 100 100 93.3 46.6 N.A. 86.6 80 N.A. N.A. 80 6.6 13.3 N.A. N.A. N.A. 60 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 93.3 93.3 N.A. N.A. 86.6 26.6 33.3 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. 37.8 N.A. 41.5 42.1 N.A.
Protein Similarity: N.A. 55.4 N.A. 62.8 63.2 N.A.
P-Site Identity: N.A. 6.6 N.A. 40 20 N.A.
P-Site Similarity: N.A. 33.3 N.A. 60 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 54 0 0 0 0 8 0 24 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 16 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 77 0 16 0 8 8 31 0 8 8 8 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 8 0 8 0 85 8 0 0 62 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 16 0 0 0 31 8 % I
% Lys: 8 0 0 0 16 0 0 8 0 0 8 54 39 0 8 % K
% Leu: 0 0 0 8 0 0 0 0 16 0 0 0 8 62 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 16 8 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 8 0 8 0 0 8 0 16 % Q
% Arg: 85 0 0 0 0 8 0 0 8 62 0 0 0 0 16 % R
% Ser: 0 16 0 24 54 70 0 70 16 0 8 16 0 0 39 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 8 % T
% Val: 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 8 0 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _