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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK1
All Species:
20
Human Site:
S58
Identified Species:
36.67
UniProt:
P00568
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00568
NP_000467.1
194
21635
S58
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
Chimpanzee
Pan troglodytes
XP_520278
232
25886
S96
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
Rhesus Macaque
Macaca mulatta
XP_001094708
194
21601
S58
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
Dog
Lupus familis
XP_547325
561
63083
R426
S
E
R
S
K
L
I
R
D
I
M
D
R
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Y5
194
21521
S58
S
E
R
G
K
K
L
S
A
I
M
E
K
G
E
Rat
Rattus norvegicus
P39069
194
21565
S58
S
S
R
G
K
M
L
S
S
I
M
E
K
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05081
194
21665
Q59
S
E
R
G
K
K
L
Q
A
I
M
E
K
G
E
Frog
Xenopus laevis
Q7ZX23
193
22088
R58
E
L
I
E
S
Y
I
R
D
G
K
I
V
P
V
Zebra Danio
Brachydanio rerio
Q7ZWE9
196
22405
K58
Q
L
I
D
S
Y
I
K
E
G
K
I
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20140
210
22579
T70
S
P
R
G
A
Q
L
T
A
I
M
E
S
G
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P43188
222
24849
E59
K
R
A
K
E
F
M
E
K
G
Q
L
V
P
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04905
202
22463
Q64
S
E
N
G
T
M
I
Q
N
M
I
K
E
G
K
Baker's Yeast
Sacchar. cerevisiae
P15700
204
22915
I66
G
S
Q
Y
G
E
L
I
K
N
C
I
K
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
98.9
20.3
N.A.
88.6
90.2
N.A.
N.A.
83.5
45.8
41.8
N.A.
N.A.
N.A.
55.2
N.A.
Protein Similarity:
100
82.3
100
28.3
N.A.
96.9
97.4
N.A.
N.A.
91.2
68
65.3
N.A.
N.A.
N.A.
70.4
N.A.
P-Site Identity:
100
100
100
40
N.A.
80
73.3
N.A.
N.A.
73.3
0
6.6
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
86.6
86.6
N.A.
N.A.
80
13.3
13.3
N.A.
N.A.
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
37.8
N.A.
41.5
42.1
N.A.
Protein Similarity:
N.A.
55.4
N.A.
62.8
63.2
N.A.
P-Site Identity:
N.A.
0
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
60
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
0
8
0
0
0
24
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
16
0
0
8
0
0
16
% D
% Glu:
8
31
0
8
8
8
0
8
31
0
0
54
8
8
24
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
62
8
0
0
0
0
24
0
0
0
70
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
31
8
0
62
8
24
0
0
0
% I
% Lys:
8
0
0
8
54
39
0
8
16
0
16
8
54
0
8
% K
% Leu:
0
16
0
0
0
8
62
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
16
8
0
0
8
62
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
24
0
% P
% Gln:
8
0
8
0
0
8
0
16
0
0
8
0
0
0
24
% Q
% Arg:
0
8
62
0
0
0
0
16
0
0
0
0
8
0
0
% R
% Ser:
70
16
0
8
16
0
0
39
8
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _