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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK1
All Species:
35.45
Human Site:
T135
Identified Species:
65
UniProt:
P00568
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00568
NP_000467.1
194
21635
T135
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Chimpanzee
Pan troglodytes
XP_520278
232
25886
T173
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Rhesus Macaque
Macaca mulatta
XP_001094708
194
21601
T135
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Dog
Lupus familis
XP_547325
561
63083
Q502
N
R
L
L
Q
R
S
Q
G
S
P
S
V
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Y5
194
21521
T135
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Rat
Rattus norvegicus
P39069
194
21565
T135
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05081
194
21665
T136
R
L
L
K
R
G
E
T
S
G
R
V
D
D
N
Frog
Xenopus laevis
Q7ZX23
193
22088
R134
C
I
E
R
C
L
E
R
G
K
S
S
G
R
S
Zebra Danio
Brachydanio rerio
Q7ZWE9
196
22405
S137
R
C
L
E
R
G
K
S
S
G
R
T
D
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20140
210
22579
T148
R
L
L
H
R
A
Q
T
S
G
R
A
D
D
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P43188
222
24849
S153
P
E
N
E
E
I
A
S
R
L
T
Q
R
F
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04905
202
22463
N138
E
K
R
L
L
G
R
N
Q
G
R
E
D
D
N
Baker's Yeast
Sacchar. cerevisiae
P15700
204
22915
T145
R
L
L
E
R
G
K
T
S
G
R
S
D
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
98.9
20.3
N.A.
88.6
90.2
N.A.
N.A.
83.5
45.8
41.8
N.A.
N.A.
N.A.
55.2
N.A.
Protein Similarity:
100
82.3
100
28.3
N.A.
96.9
97.4
N.A.
N.A.
91.2
68
65.3
N.A.
N.A.
N.A.
70.4
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
100
6.6
66.6
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
100
26.6
86.6
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
37.8
N.A.
41.5
42.1
N.A.
Protein Similarity:
N.A.
55.4
N.A.
62.8
63.2
N.A.
P-Site Identity:
N.A.
0
N.A.
40
80
N.A.
P-Site Similarity:
N.A.
20
N.A.
40
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% A
% Cys:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
77
77
16
% D
% Glu:
8
8
8
24
8
0
54
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
70
0
0
16
77
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
47
0
0
16
0
0
8
0
0
0
0
0
% K
% Leu:
0
62
77
16
8
8
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
77
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
8
8
0
0
8
0
0
0
% Q
% Arg:
70
8
8
8
70
8
8
8
8
0
77
0
8
8
0
% R
% Ser:
0
0
0
0
0
0
8
16
70
8
8
24
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
62
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
47
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _