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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK1
All Species:
39.7
Human Site:
T145
Identified Species:
72.78
UniProt:
P00568
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00568
NP_000467.1
194
21635
T145
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Chimpanzee
Pan troglodytes
XP_520278
232
25886
T183
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001094708
194
21601
T145
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Dog
Lupus familis
XP_547325
561
63083
T512
P
S
V
E
D
T
T
T
I
A
K
R
L
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Y5
194
21521
T145
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Rat
Rattus norvegicus
P39069
194
21565
T145
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05081
194
21665
T146
R
V
D
D
N
E
E
T
I
K
K
R
L
E
T
Frog
Xenopus laevis
Q7ZX23
193
22088
N144
S
S
G
R
S
D
D
N
R
E
S
L
E
K
R
Zebra Danio
Brachydanio rerio
Q7ZWE9
196
22405
S147
R
T
D
D
N
R
E
S
L
E
K
R
I
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20140
210
22579
T158
R
A
D
D
N
A
D
T
I
K
K
R
L
H
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P43188
222
24849
E163
T
Q
R
F
D
D
T
E
E
K
V
K
L
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04905
202
22463
T148
R
E
D
D
N
I
E
T
I
R
K
R
F
K
V
Baker's Yeast
Sacchar. cerevisiae
P15700
204
22915
S155
R
S
D
D
N
I
E
S
I
K
K
R
F
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
98.9
20.3
N.A.
88.6
90.2
N.A.
N.A.
83.5
45.8
41.8
N.A.
N.A.
N.A.
55.2
N.A.
Protein Similarity:
100
82.3
100
28.3
N.A.
96.9
97.4
N.A.
N.A.
91.2
68
65.3
N.A.
N.A.
N.A.
70.4
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
100
100
N.A.
N.A.
100
0
53.3
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
60
N.A.
100
100
N.A.
N.A.
100
33.3
86.6
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
37.8
N.A.
41.5
42.1
N.A.
Protein Similarity:
N.A.
55.4
N.A.
62.8
63.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
77
77
16
16
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
47
70
8
8
16
0
0
8
54
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
16
0
0
77
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
70
85
8
0
16
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
8
70
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
77
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
77
0
8
8
0
8
0
0
8
8
0
85
0
8
8
% R
% Ser:
8
24
0
0
8
0
0
16
0
0
8
0
0
0
0
% S
% Thr:
8
8
0
0
0
8
16
70
0
0
0
0
0
0
77
% T
% Val:
0
47
8
0
0
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _