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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK1 All Species: 39.7
Human Site: T23 Identified Species: 72.78
UniProt: P00568 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00568 NP_000467.1 194 21635 T23 G P G S G K G T Q C E K I V Q
Chimpanzee Pan troglodytes XP_520278 232 25886 T61 G P G S G K G T Q C E K I V Q
Rhesus Macaque Macaca mulatta XP_001094708 194 21601 T23 G P G S G K G T Q C E K I V Q
Dog Lupus familis XP_547325 561 63083 T391 G P G S G K G T Q C E K L V E
Cat Felis silvestris
Mouse Mus musculus Q9R0Y5 194 21521 T23 G P G S G K G T Q C E K I V Q
Rat Rattus norvegicus P39069 194 21565 T23 G P G S G K G T Q C E K I V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P05081 194 21665 T24 G P G S G K G T Q C E K I V H
Frog Xenopus laevis Q7ZX23 193 22088 I23 K G T Q C E R I V Q K Y G Y T
Zebra Danio Brachydanio rerio Q7ZWE9 196 22405 I23 K G T Q C A R I V E N Y S Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20140 210 22579 T35 G P G S G K G T Q C D K I V A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P43188 222 24849 L24 G K G T Q C E L I K T K Y Q L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04905 202 22463 T29 G P G S G K G T Q C A Y I V E
Baker's Yeast Sacchar. cerevisiae P15700 204 22915 T31 G P G A G K G T Q C E K L V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.1 98.9 20.3 N.A. 88.6 90.2 N.A. N.A. 83.5 45.8 41.8 N.A. N.A. N.A. 55.2 N.A.
Protein Similarity: 100 82.3 100 28.3 N.A. 96.9 97.4 N.A. N.A. 91.2 68 65.3 N.A. N.A. N.A. 70.4 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. N.A. 93.3 0 0 N.A. N.A. N.A. 86.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 13.3 0 N.A. N.A. N.A. 93.3 N.A.
Percent
Protein Identity: N.A. 37.8 N.A. 41.5 42.1 N.A.
Protein Similarity: N.A. 55.4 N.A. 62.8 63.2 N.A.
P-Site Identity: N.A. 20 N.A. 80 80 N.A.
P-Site Similarity: N.A. 26.6 N.A. 86.6 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 16 8 0 0 0 77 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 0 0 8 62 0 0 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 85 16 85 0 77 0 77 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 16 8 0 0 0 62 0 0 % I
% Lys: 16 8 0 0 0 77 0 0 0 8 8 77 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 0 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 16 8 0 0 0 77 8 0 0 0 8 39 % Q
% Arg: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 70 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 0 0 16 8 0 0 0 77 0 0 8 0 0 0 16 % T
% Val: 0 0 0 0 0 0 0 0 16 0 0 0 0 77 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 24 8 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _