KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK1
All Species:
22.73
Human Site:
T71
Identified Species:
41.67
UniProt:
P00568
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00568
NP_000467.1
194
21635
T71
G
Q
L
V
P
L
E
T
V
L
D
M
L
R
D
Chimpanzee
Pan troglodytes
XP_520278
232
25886
T109
G
Q
L
V
P
L
E
T
V
L
D
M
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001094708
194
21601
T71
G
Q
L
V
P
L
E
T
V
L
D
M
L
R
D
Dog
Lupus familis
XP_547325
561
63083
I439
G
D
P
V
P
S
G
I
I
L
E
L
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Y5
194
21521
T71
G
E
L
V
P
L
D
T
V
L
D
M
L
R
D
Rat
Rattus norvegicus
P39069
194
21565
T71
G
E
L
V
P
L
E
T
V
L
D
M
L
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05081
194
21665
T72
G
E
L
V
P
L
D
T
V
L
D
M
L
R
D
Frog
Xenopus laevis
Q7ZX23
193
22088
L71
P
V
E
I
T
I
S
L
L
Q
R
A
M
E
R
Zebra Danio
Brachydanio rerio
Q7ZWE9
196
22405
L71
P
V
Q
I
T
I
N
L
L
R
K
A
M
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20140
210
22579
V83
G
A
L
V
P
L
E
V
V
L
D
L
V
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P43188
222
24849
M72
P
D
E
I
V
V
N
M
V
K
E
R
L
R
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04905
202
22463
V77
G
K
I
V
P
S
E
V
T
I
K
L
L
Q
K
Baker's Yeast
Sacchar. cerevisiae
P15700
204
22915
E79
E
G
Q
I
V
P
Q
E
I
T
L
A
L
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
98.9
20.3
N.A.
88.6
90.2
N.A.
N.A.
83.5
45.8
41.8
N.A.
N.A.
N.A.
55.2
N.A.
Protein Similarity:
100
82.3
100
28.3
N.A.
96.9
97.4
N.A.
N.A.
91.2
68
65.3
N.A.
N.A.
N.A.
70.4
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
86.6
93.3
N.A.
N.A.
86.6
0
0
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
100
100
N.A.
N.A.
100
26.6
33.3
N.A.
N.A.
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
37.8
N.A.
41.5
42.1
N.A.
Protein Similarity:
N.A.
55.4
N.A.
62.8
63.2
N.A.
P-Site Identity:
N.A.
20
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
16
0
0
0
54
0
0
0
47
% D
% Glu:
8
24
16
0
0
0
47
8
0
0
16
0
0
16
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
31
0
16
0
8
16
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
16
0
0
16
8
% K
% Leu:
0
0
54
0
0
54
0
16
16
62
8
24
77
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
47
16
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
24
0
8
0
70
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
24
16
0
0
0
8
0
0
8
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
8
0
54
16
% R
% Ser:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
16
0
0
47
8
8
0
0
0
0
0
% T
% Val:
0
16
0
70
16
8
0
16
62
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _