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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK1
All Species:
27.58
Human Site:
Y95
Identified Species:
50.56
UniProt:
P00568
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00568
NP_000467.1
194
21635
Y95
K
G
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
Chimpanzee
Pan troglodytes
XP_520278
232
25886
Y133
K
G
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
Rhesus Macaque
Macaca mulatta
XP_001094708
194
21601
Y95
K
G
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
Dog
Lupus familis
XP_547325
561
63083
Y463
K
G
F
L
I
D
G
Y
P
Q
E
V
K
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Y5
194
21521
Y95
N
G
F
L
I
D
G
Y
P
R
E
V
K
Q
G
Rat
Rattus norvegicus
P39069
194
21565
Y95
N
G
F
L
I
D
G
Y
P
R
E
V
K
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05081
194
21665
Y96
K
G
F
L
I
D
G
Y
P
R
E
V
K
Q
G
Frog
Xenopus laevis
Q7ZX23
193
22088
P95
K
F
L
I
D
G
F
P
R
N
E
D
N
L
Q
Zebra Danio
Brachydanio rerio
Q7ZWE9
196
22405
P95
R
F
L
I
D
G
F
P
R
N
Q
D
N
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20140
210
22579
G107
S
K
G
F
L
I
D
G
Y
P
R
E
V
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P43188
222
24849
Y96
L
D
G
Y
P
R
S
Y
S
Q
A
M
A
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04905
202
22463
R101
F
L
I
D
G
F
P
R
N
E
E
N
R
A
A
Baker's Yeast
Sacchar. cerevisiae
P15700
204
22915
D103
N
K
H
K
F
L
I
D
G
F
P
R
K
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
98.9
20.3
N.A.
88.6
90.2
N.A.
N.A.
83.5
45.8
41.8
N.A.
N.A.
N.A.
55.2
N.A.
Protein Similarity:
100
82.3
100
28.3
N.A.
96.9
97.4
N.A.
N.A.
91.2
68
65.3
N.A.
N.A.
N.A.
70.4
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
93.3
13.3
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
20
20
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
37.8
N.A.
41.5
42.1
N.A.
Protein Similarity:
N.A.
55.4
N.A.
62.8
63.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
16
54
8
8
0
0
0
16
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
70
8
0
0
8
% E
% Phe:
8
16
54
8
8
8
16
0
0
8
0
0
0
0
0
% F
% Gly:
0
54
16
0
8
16
54
8
8
0
0
0
0
0
54
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
16
54
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
47
16
0
8
0
0
0
0
0
0
0
0
39
0
0
% K
% Leu:
8
8
16
54
8
8
0
0
0
0
0
0
0
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
24
0
0
0
0
0
0
0
8
16
0
8
16
0
0
% N
% Pro:
0
0
0
0
8
0
8
16
54
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
8
0
24
54
24
% Q
% Arg:
8
0
0
0
0
8
0
8
16
47
8
8
8
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
54
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
62
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _