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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
6.97
Human Site:
S182
Identified Species:
12.78
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S182
T
V
R
R
Q
E
C
S
I
P
V
C
G
Q
D
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
S49
N
R
P
K
R
Y
N
S
G
K
L
E
E
F
V
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
S190
T
V
R
R
E
E
C
S
I
P
V
C
G
Q
D
Dog
Lupus familis
XP_855946
493
54567
W81
T
A
K
T
M
E
F
W
N
K
Y
K
D
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
V184
V
R
R
E
E
C
S
V
P
V
C
G
Q
E
G
Rat
Rattus norvegicus
P18292
617
70393
I184
V
R
R
E
E
C
S
I
P
V
C
G
Q
E
G
Wallaby
Macropus eugenll
O18783
806
90963
D177
D
I
R
Y
E
Y
C
D
V
P
E
C
E
D
E
Platypus
Ornith. anatinus
XP_001511876
701
76014
E269
R
P
R
G
S
K
P
E
R
P
K
G
P
C
L
Chicken
Gallus gallus
P25155
475
53123
S63
E
C
N
E
E
R
C
S
K
E
E
A
R
E
A
Frog
Xenopus laevis
NP_001086517
607
69214
P172
P
W
C
Y
T
T
D
P
Q
K
Q
W
E
E
C
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
D112
I
C
A
T
T
E
G
D
C
F
I
N
I
G
A
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
V180
C
F
T
T
D
P
T
V
Q
K
E
T
C
R
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
A282
M
V
K
G
L
L
K
A
D
K
L
T
G
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
93.3
20
N.A.
6.6
6.6
26.6
13.3
13.3
0
6.6
0
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
26.6
N.A.
20
20
53.3
20
26.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
0
0
0
8
0
0
16
% A
% Cys:
8
16
8
0
0
16
31
0
8
0
16
24
8
8
8
% C
% Asp:
8
0
0
0
8
0
8
16
8
0
0
0
8
8
24
% D
% Glu:
8
0
0
24
39
31
0
8
0
8
24
8
24
31
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
16
0
0
8
0
8
0
0
24
24
16
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
16
0
8
0
8
0
0
% I
% Lys:
0
0
16
8
0
8
8
0
8
39
8
8
0
0
0
% K
% Leu:
0
0
0
0
8
8
0
0
0
0
16
0
0
0
8
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
8
0
8
0
0
8
0
0
8
% N
% Pro:
8
8
8
0
0
8
8
8
16
31
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
16
0
8
0
16
24
0
% Q
% Arg:
8
24
47
16
8
8
0
0
8
0
0
0
8
8
0
% R
% Ser:
0
0
0
0
8
0
16
31
0
0
0
0
0
0
0
% S
% Thr:
24
0
8
24
16
8
8
0
0
0
0
16
0
0
0
% T
% Val:
16
24
0
0
0
0
0
16
8
16
16
0
0
0
16
% V
% Trp:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
16
0
16
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _