Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 8.18
Human Site: S207 Identified Species: 15
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 S207 E G S S V N L S P P L E Q C V
Chimpanzee Pan troglodytes Q95ND7 461 51746 A74 E K C S F E E A R E V F E N T
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 S215 S V N L S L P S E E C V P D R
Dog Lupus familis XP_855946 493 54567 L106 G Q C K D G L L E Y S C I C L
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 S209 G G S K D N L S P P L G Q C L
Rat Rattus norvegicus P18292 617 70393 S209 R G S K E N L S P P L G E C L
Wallaby Macropus eugenll O18783 806 90963 S202 G T I S K T E S G I E C Q P W
Platypus Ornith. anatinus XP_001511876 701 76014 A294 Q A T T L S G A P C L P W A S
Chicken Gallus gallus P25155 475 53123 D88 W N I Y V D G D Q C S S N P C
Frog Xenopus laevis NP_001086517 607 69214 N197 T V E P L L V N V K E S V T R
Zebra Danio Brachydanio rerio NP_998555 524 59542 W137 S G K A C Q Y W K S N F P H K
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 K205 T P T P K H F K T I Q S S C I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 V307 R P N A L F A V T N A S L P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 13.3 6.6 13.3 N.A. 66.6 60 20 13.3 6.6 0 6.6 6.6 N.A. N.A. N.A. 0
P-Site Similarity: 100 33.3 13.3 20 N.A. 73.3 73.3 20 53.3 13.3 20 13.3 26.6 N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 0 8 16 0 0 8 0 0 8 0 % A
% Cys: 0 0 16 0 8 0 0 0 0 16 8 16 0 39 8 % C
% Asp: 0 0 0 0 16 8 0 8 0 0 0 0 0 8 0 % D
% Glu: 16 0 8 0 8 8 16 0 16 16 16 8 16 0 0 % E
% Phe: 0 0 0 0 8 8 8 0 0 0 0 16 0 0 0 % F
% Gly: 24 31 0 0 0 8 16 0 8 0 0 16 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 16 0 0 0 0 0 0 16 0 0 8 0 8 % I
% Lys: 0 8 8 24 16 0 0 8 8 8 0 0 0 0 8 % K
% Leu: 0 0 0 8 24 16 31 8 0 0 31 0 8 0 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 0 0 24 0 8 0 8 8 0 8 8 0 % N
% Pro: 0 16 0 16 0 0 8 0 31 24 0 8 16 24 0 % P
% Gln: 8 8 0 0 0 8 0 0 8 0 8 0 24 0 0 % Q
% Arg: 16 0 0 0 0 0 0 0 8 0 0 0 0 0 16 % R
% Ser: 16 0 24 24 8 8 0 39 0 8 16 31 8 0 16 % S
% Thr: 16 8 16 8 0 8 0 0 16 0 0 0 0 8 8 % T
% Val: 0 16 0 0 16 0 8 8 8 0 8 8 8 0 8 % V
% Trp: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % W
% Tyr: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _