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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
3.33
Human Site:
S253
Identified Species:
6.11
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S253
S
K
H
Q
D
F
N
S
A
V
Q
L
V
E
N
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
P120
N
S
Y
E
C
W
C
P
F
G
F
E
G
K
N
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Q261
Q
D
F
D
S
A
V
Q
L
V
E
N
F
C
R
Dog
Lupus familis
XP_855946
493
54567
A152
S
S
V
V
C
S
C
A
S
G
Y
I
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
P255
S
K
Y
Q
D
F
D
P
E
V
K
L
V
E
N
Rat
Rattus norvegicus
P18292
617
70393
P255
S
K
Y
Q
N
F
D
P
E
V
K
L
V
Q
N
Wallaby
Macropus eugenll
O18783
806
90963
S248
P
R
P
W
C
F
T
S
N
P
E
K
R
W
E
Platypus
Ornith. anatinus
XP_001511876
701
76014
G340
G
I
W
C
Y
V
D
G
P
P
G
S
Y
E
Y
Chicken
Gallus gallus
P25155
475
53123
G134
K
Y
C
K
I
N
N
G
D
C
E
Q
F
C
S
Frog
Xenopus laevis
NP_001086517
607
69214
D243
V
Q
Q
Y
G
R
K
D
F
I
P
E
V
K
L
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
T183
D
P
T
V
R
R
E
T
C
N
V
P
K
C
G
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
P251
S
Q
N
K
E
F
N
P
D
I
N
L
L
C
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
T353
D
L
A
Q
D
G
V
T
C
V
S
E
L
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
6.6
6.6
N.A.
66.6
53.3
13.3
6.6
6.6
6.6
0
33.3
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
40
13.3
40
N.A.
86.6
86.6
26.6
13.3
26.6
26.6
6.6
73.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
8
8
24
0
16
0
16
8
0
0
0
31
0
% C
% Asp:
16
8
0
8
24
0
24
8
16
0
0
0
0
8
8
% D
% Glu:
0
0
0
8
8
0
8
0
16
0
24
24
0
24
8
% E
% Phe:
0
0
8
0
0
39
0
0
16
0
8
0
16
0
0
% F
% Gly:
8
0
0
0
8
8
0
16
0
16
8
0
8
8
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
16
0
8
0
0
8
% I
% Lys:
8
24
0
16
0
0
8
0
0
0
16
8
8
16
0
% K
% Leu:
0
8
0
0
0
0
0
0
8
0
0
31
24
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
8
24
0
8
8
8
8
0
0
39
% N
% Pro:
8
8
8
0
0
0
0
31
8
16
8
8
0
0
0
% P
% Gln:
8
16
8
31
0
0
0
8
0
0
8
8
0
8
0
% Q
% Arg:
0
8
0
0
8
16
0
0
0
0
0
0
8
0
8
% R
% Ser:
39
16
0
0
8
8
0
16
8
0
8
8
0
0
8
% S
% Thr:
0
0
8
0
0
0
8
16
0
0
0
0
0
0
0
% T
% Val:
8
0
8
16
0
8
16
0
0
39
8
0
31
0
0
% V
% Trp:
0
0
8
8
0
8
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
24
8
8
0
0
0
0
0
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _