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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
19.09
Human Site:
S346
Identified Species:
35
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S346
R
P
L
F
E
K
K
S
L
E
D
K
T
E
R
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
E206
V
D
Y
V
N
S
T
E
A
E
T
I
L
D
N
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
S351
R
P
L
F
E
K
K
S
L
E
D
K
T
E
G
Dog
Lupus familis
XP_855946
493
54567
V238
D
E
D
A
S
G
L
V
R
I
V
G
G
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
S343
R
P
L
F
E
K
K
S
L
K
D
T
T
E
K
Rat
Rattus norvegicus
P18292
617
70393
S342
R
P
L
F
E
K
K
S
L
T
D
K
T
E
K
Wallaby
Macropus eugenll
O18783
806
90963
T406
T
P
H
Q
H
K
K
T
P
D
N
F
P
N
A
Platypus
Ornith. anatinus
XP_001511876
701
76014
A427
R
R
G
E
A
Q
V
A
A
R
G
R
R
G
S
Chicken
Gallus gallus
P25155
475
53123
E220
E
V
F
T
T
T
T
E
S
P
T
P
P
P
R
Frog
Xenopus laevis
NP_001086517
607
69214
S331
R
P
L
F
E
Q
K
S
V
E
D
K
S
E
K
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
A269
R
I
V
G
G
D
E
A
E
V
A
S
A
P
W
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
N340
R
P
L
F
E
Q
K
N
K
K
D
A
S
E
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
V689
I
T
E
V
C
G
T
V
T
S
P
E
A
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
93.3
0
N.A.
80
86.6
20
6.6
6.6
73.3
6.6
53.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
93.3
6.6
N.A.
93.3
93.3
40
26.6
6.6
100
26.6
80
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
16
16
0
8
8
16
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
8
0
0
0
8
47
0
0
8
16
% D
% Glu:
8
8
8
8
47
0
8
16
8
31
0
8
0
47
0
% E
% Phe:
0
0
8
47
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
8
8
16
0
0
0
0
8
8
8
8
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
39
54
0
8
16
0
31
0
0
24
% K
% Leu:
0
0
47
0
0
0
8
0
31
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
8
% N
% Pro:
0
54
0
0
0
0
0
0
8
8
8
8
16
16
0
% P
% Gln:
0
0
0
8
0
24
0
0
0
0
0
0
0
8
0
% Q
% Arg:
62
8
0
0
0
0
0
0
8
8
0
8
8
0
16
% R
% Ser:
0
0
0
0
8
8
0
39
8
8
0
8
16
0
8
% S
% Thr:
8
8
0
8
8
8
24
8
8
8
16
8
31
8
0
% T
% Val:
8
8
8
16
0
0
8
16
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _