KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
20.3
Human Site:
S430
Identified Species:
37.22
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
S430
L
V
R
I
G
K
H
S
R
T
R
Y
E
R
N
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
T290
N
I
E
E
T
E
H
T
E
Q
K
R
N
V
I
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
S435
L
V
R
I
G
K
H
S
R
T
R
Y
E
R
N
Dog
Lupus familis
XP_855946
493
54567
N322
Y
P
K
Y
Y
Y
F
N
H
N
K
F
V
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
S427
L
V
R
I
G
K
H
S
R
T
R
Y
E
R
N
Rat
Rattus norvegicus
P18292
617
70393
S426
L
V
R
I
G
K
H
S
R
T
R
Y
E
R
N
Wallaby
Macropus eugenll
O18783
806
90963
T490
D
Y
R
G
K
R
S
T
T
V
T
G
T
L
C
Platypus
Ornith. anatinus
XP_001511876
701
76014
V511
R
P
P
R
P
S
G
V
R
G
R
Y
E
R
T
Chicken
Gallus gallus
P25155
475
53123
H304
V
D
R
E
K
E
E
H
S
E
T
T
H
T
A
Frog
Xenopus laevis
NP_001086517
607
69214
Y415
L
V
R
I
G
K
H
Y
R
T
K
Y
E
R
A
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
N353
I
I
V
H
P
K
Y
N
W
K
E
N
L
N
R
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
N424
L
V
R
L
G
K
H
N
R
A
K
F
E
Q
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
S773
G
D
H
D
T
L
T
S
E
D
H
Q
V
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
6.6
33.3
6.6
80
6.6
53.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
33.3
N.A.
100
100
20
33.3
20
86.6
33.3
86.6
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
16
0
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
16
0
16
8
0
16
8
8
0
54
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
16
0
0
0
% F
% Gly:
8
0
0
8
47
0
8
0
0
8
0
8
0
0
8
% G
% His:
0
0
8
8
0
0
54
8
8
0
8
0
8
0
0
% H
% Ile:
8
16
0
39
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
8
0
16
54
0
0
0
8
31
0
0
0
0
% K
% Leu:
47
0
0
8
0
8
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
24
0
8
0
8
8
8
31
% N
% Pro:
0
16
8
0
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
8
0
62
8
0
8
0
0
54
0
39
8
0
54
8
% R
% Ser:
0
0
0
0
0
8
8
39
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
16
0
8
16
8
39
16
8
8
8
8
% T
% Val:
8
47
8
0
0
0
0
8
0
8
0
0
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
8
8
8
8
0
0
0
47
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _