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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
17.27
Human Site:
T145
Identified Species:
31.67
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
T145
H
K
P
E
I
N
S
T
T
H
P
G
A
D
L
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
G13
M
I
M
A
E
S
P
G
L
I
T
I
C
L
L
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
T153
H
K
P
E
I
N
S
T
T
H
P
G
A
D
L
Dog
Lupus familis
XP_855946
493
54567
L45
V
R
R
A
N
S
F
L
E
E
M
K
K
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
T146
H
K
P
E
I
N
S
T
T
H
P
G
A
D
L
Rat
Rattus norvegicus
P18292
617
70393
T146
H
R
P
D
I
N
S
T
T
H
P
G
A
D
L
Wallaby
Macropus eugenll
O18783
806
90963
S140
H
V
P
N
Y
A
P
S
K
Y
P
D
A
G
L
Platypus
Ornith. anatinus
XP_001511876
701
76014
R225
T
Y
T
G
E
R
R
R
P
G
P
P
A
P
T
Chicken
Gallus gallus
P25155
475
53123
K27
A
E
G
G
V
F
I
K
K
E
S
A
D
K
F
Frog
Xenopus laevis
NP_001086517
607
69214
Y136
C
Q
Y
W
I
S
N
Y
P
H
K
T
K
F
S
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
D76
R
E
V
F
E
R
V
D
K
T
E
I
F
W
A
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
I143
K
H
S
F
P
H
P
I
M
R
E
Y
N
A
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
G217
T
G
L
R
W
T
N
G
L
A
I
D
F
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
100
0
N.A.
100
86.6
33.3
13.3
0
13.3
0
0
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
46.6
13.3
13.3
33.3
6.6
6.6
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
8
0
0
0
8
0
8
47
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
0
0
0
16
8
31
0
% D
% Glu:
0
16
0
24
24
0
0
0
8
16
16
0
0
8
8
% E
% Phe:
0
0
0
16
0
8
8
0
0
0
0
0
16
8
8
% F
% Gly:
0
8
8
16
0
0
0
16
0
8
0
31
0
16
0
% G
% His:
39
8
0
0
0
8
0
0
0
39
0
0
0
0
0
% H
% Ile:
0
8
0
0
39
0
8
8
0
8
8
16
0
0
0
% I
% Lys:
8
24
0
0
0
0
0
8
24
0
8
8
16
8
0
% K
% Leu:
0
0
8
0
0
0
0
8
16
0
0
0
0
8
47
% L
% Met:
8
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
8
31
16
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
39
0
8
0
24
0
16
0
47
8
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
8
8
0
16
8
8
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
24
31
8
0
0
8
0
0
0
16
% S
% Thr:
16
0
8
0
0
8
0
31
31
8
8
8
0
0
8
% T
% Val:
8
8
8
0
8
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
8
0
8
0
0
8
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _