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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 20.3
Human Site: T328 Identified Species: 37.22
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 T328 Q T F F N P R T F G S G E A D
Chimpanzee Pan troglodytes Q95ND7 461 51746 K188 V S V S Q T S K L T R A E T V
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 T333 Q T F F D P R T F G L G E A D
Dog Lupus familis XP_855946 493 54567 L220 P T Q S T M F L L P F N Q T N
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 T325 H T F F N E K T F G L G E A D
Rat Rattus norvegicus P18292 617 70393 T324 H T F F D E R T F G L G E A D
Wallaby Macropus eugenll O18783 806 90963 S388 G T T S T T I S G K K C Q A W
Platypus Ornith. anatinus XP_001511876 701 76014 R409 S G P A F P A R G P G R V A G
Chicken Gallus gallus P25155 475 53123 D202 T N A T S D Q D V P S T N G S
Frog Xenopus laevis NP_001086517 607 69214 T313 Q I F F D E K T F G S G E A E
Zebra Danio Brachydanio rerio NP_998555 524 59542 E251 I N K A D K N E K E L L M S Y
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 T322 K R F F N P R T F G E G E D E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 V671 E A Y A W L T V A D T M N P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 6.6 86.6 6.6 N.A. 73.3 73.3 13.3 13.3 6.6 66.6 0 66.6 N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 93.3 20 N.A. 80 80 26.6 13.3 20 86.6 13.3 80 N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 24 0 0 8 0 8 0 0 8 0 54 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 31 8 0 8 0 8 0 0 0 8 31 % D
% Glu: 8 0 0 0 0 24 0 8 0 8 8 0 54 0 16 % E
% Phe: 0 0 47 47 8 0 8 0 47 0 8 0 0 0 0 % F
% Gly: 8 8 0 0 0 0 0 0 16 47 8 47 0 8 8 % G
% His: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 8 16 8 8 8 8 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 8 16 0 31 8 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % M
% Asn: 0 16 0 0 24 0 8 0 0 0 0 8 16 0 8 % N
% Pro: 8 0 8 0 0 31 0 0 0 24 0 0 0 8 8 % P
% Gln: 24 0 8 0 8 0 8 0 0 0 0 0 16 0 0 % Q
% Arg: 0 8 0 0 0 0 31 8 0 0 8 8 0 0 0 % R
% Ser: 8 8 0 24 8 0 8 8 0 0 24 0 0 8 8 % S
% Thr: 8 47 8 8 16 16 8 47 0 8 8 8 0 16 0 % T
% Val: 8 0 8 0 0 0 0 8 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _