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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
23.94
Human Site:
T540
Identified Species:
43.89
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
T540
R
P
V
C
K
D
S
T
R
I
R
I
T
D
N
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
I390
L
R
S
T
K
F
T
I
Y
N
N
M
F
C
A
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
T545
R
S
V
C
K
D
S
T
R
I
R
I
T
D
N
Dog
Lupus familis
XP_855946
493
54567
K422
F
C
A
G
Y
D
S
K
P
E
D
A
C
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
T537
R
P
V
C
K
A
S
T
R
I
R
I
T
D
N
Rat
Rattus norvegicus
P18292
617
70393
T536
R
P
V
C
K
A
S
T
R
I
R
I
T
D
N
Wallaby
Macropus eugenll
O18783
806
90963
N726
V
I
D
N
R
V
C
N
R
H
E
Y
L
N
G
Platypus
Ornith. anatinus
XP_001511876
701
76014
T619
Q
D
V
C
R
A
S
T
R
I
K
V
T
D
N
Chicken
Gallus gallus
P25155
475
53123
I404
K
Q
S
T
N
F
A
I
T
E
N
M
F
C
A
Frog
Xenopus laevis
NP_001086517
607
69214
T524
Q
E
T
C
K
S
S
T
K
I
K
I
T
D
N
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
P453
M
F
C
A
G
Y
Q
P
D
D
S
K
R
G
D
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
T533
Q
D
V
C
R
S
S
T
S
I
R
I
T
D
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
V876
K
D
A
T
T
F
E
V
T
R
Y
M
F
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
93.3
13.3
N.A.
93.3
93.3
6.6
60
0
60
0
66.6
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
93.3
13.3
N.A.
93.3
93.3
20
86.6
20
80
6.6
80
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
24
8
0
0
0
0
8
0
0
24
% A
% Cys:
0
8
8
54
0
0
8
0
0
0
0
0
8
24
0
% C
% Asp:
0
24
8
0
0
24
0
0
8
8
8
0
0
54
8
% D
% Glu:
0
8
0
0
0
0
8
0
0
16
8
0
0
0
0
% E
% Phe:
8
8
0
0
0
24
0
0
0
0
0
0
24
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
16
0
54
0
47
0
0
0
% I
% Lys:
16
0
0
0
47
0
0
8
8
0
16
8
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
0
8
16
0
0
8
54
% N
% Pro:
0
24
0
0
0
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
24
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
31
8
0
0
24
0
0
0
47
8
39
0
8
0
0
% R
% Ser:
0
8
16
0
0
16
62
0
8
0
8
0
0
0
0
% S
% Thr:
0
0
8
24
8
0
8
54
16
0
0
0
54
0
0
% T
% Val:
8
0
47
0
0
8
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _