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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 5.76
Human Site: T95 Identified Species: 10.56
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 T95 T A C E T A R T P R D K L A A
Chimpanzee Pan troglodytes Q95ND7 461 51746
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 T103 T A C E T A R T S R D T L A A
Dog Lupus familis XP_855946 493 54567
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 K96 T V C D S V R K P R E T F M D
Rat Rattus norvegicus P18292 617 70393 K96 T V C D S V R K P R E T F M D
Wallaby Macropus eugenll O18783 806 90963 V92 V E R K R D V V L F E K R I Y
Platypus Ornith. anatinus XP_001511876 701 76014 K175 S A C T V T K K P R E S R D L
Chicken Gallus gallus P25155 475 53123
Frog Xenopus laevis NP_001086517 607 69214 P90 V K Y K D C E P D K K S R D A
Zebra Danio Brachydanio rerio NP_998555 524 59542 N30 C H N V F I N N K E A S Q I I
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 L93 L D C N G N Q L P R T E A N I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 T166 S D R K T L V T N I A K P R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 0 86.6 0 N.A. 33.3 33.3 6.6 26.6 0 6.6 0 20 N.A. N.A. N.A. 26.6
P-Site Similarity: 100 0 86.6 0 N.A. 53.3 53.3 20 46.6 0 20 0 33.3 N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 16 0 0 0 0 16 0 8 16 31 % A
% Cys: 8 0 47 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 16 8 8 0 0 8 0 16 0 0 16 16 % D
% Glu: 0 8 0 16 0 0 8 0 0 8 31 8 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 8 0 0 16 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 0 0 0 16 16 % I
% Lys: 0 8 0 24 0 0 8 24 8 8 8 24 0 0 0 % K
% Leu: 8 0 0 0 0 8 0 8 8 0 0 0 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % M
% Asn: 0 0 8 8 0 8 8 8 8 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 8 39 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 16 0 8 0 31 0 0 47 0 0 24 8 0 % R
% Ser: 16 0 0 0 16 0 0 0 8 0 0 24 0 0 0 % S
% Thr: 31 0 0 8 24 8 0 24 0 0 8 24 0 0 0 % T
% Val: 16 16 0 8 8 16 16 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _