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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
5.45
Human Site:
Y275
Identified Species:
10
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
Y275
D
E
E
G
V
W
C
Y
V
A
G
K
P
G
D
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
N135
C
E
L
D
V
T
C
N
I
K
N
G
R
C
E
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Y280
D
E
E
G
V
W
C
Y
V
A
G
K
P
G
D
Dog
Lupus familis
XP_855946
493
54567
T167
N
G
K
S
C
I
S
T
E
P
F
P
C
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
E272
R
N
P
D
W
D
E
E
G
A
W
C
Y
V
A
Rat
Rattus norvegicus
P18292
617
70393
E271
C
R
N
P
D
R
D
E
E
G
A
W
C
F
V
Wallaby
Macropus eugenll
O18783
806
90963
C335
D
G
E
L
E
P
W
C
Y
T
T
N
P
D
V
Platypus
Ornith. anatinus
XP_001511876
701
76014
R356
P
A
V
Y
C
G
E
R
R
E
A
G
R
P
G
Chicken
Gallus gallus
P25155
475
53123
D149
I
K
K
S
V
Q
K
D
V
V
C
S
C
T
S
Frog
Xenopus laevis
NP_001086517
607
69214
N260
N
Y
C
R
N
P
D
N
D
G
E
G
L
W
C
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
K198
E
A
V
V
P
P
P
K
A
P
L
D
K
F
V
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
G269
N
P
D
K
D
P
E
G
P
W
C
Y
V
N
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
K618
I
D
S
V
T
W
W
K
D
G
S
R
V
H
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
20
100
6.6
N.A.
6.6
0
20
0
13.3
0
0
0
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
20
N.A.
6.6
0
20
0
26.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
8
24
16
0
0
0
16
% A
% Cys:
16
0
8
0
16
0
24
8
0
0
16
8
24
8
8
% C
% Asp:
24
8
8
16
16
8
16
8
16
0
0
8
0
8
16
% D
% Glu:
8
24
24
0
8
0
24
16
16
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% F
% Gly:
0
16
0
16
0
8
0
8
8
24
16
24
0
24
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
16
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
16
8
0
0
8
16
0
8
0
16
8
0
8
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
8
8
0
8
0
0
16
0
0
8
8
0
8
0
% N
% Pro:
8
8
8
8
8
31
8
0
8
16
0
8
24
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
8
0
8
0
8
0
8
8
0
0
8
16
0
0
% R
% Ser:
0
0
8
16
0
0
8
0
0
0
8
8
0
0
8
% S
% Thr:
0
0
0
0
8
8
0
8
0
8
8
0
0
8
0
% T
% Val:
0
0
16
16
31
0
0
0
24
8
0
0
16
8
24
% V
% Trp:
0
0
0
0
8
24
16
0
0
8
8
8
0
8
0
% W
% Tyr:
0
8
0
8
0
0
0
16
8
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _