Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 4.85
Human Site: Y285 Identified Species: 8.89
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 Y285 G K P G D F G Y C D L N Y C E
Chimpanzee Pan troglodytes Q95ND7 461 51746 C145 N G R C E Q F C K N S A D N K
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 Y290 G K P G D F E Y C D L N Y C E
Dog Lupus familis XP_855946 493 54567 V177 F P C G K T T V G R R K R A T
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 P282 W C Y V A G Q P G D F E Y C N
Rat Rattus norvegicus P18292 617 70393 Q281 A W C F V A Q Q P G F E Y C S
Wallaby Macropus eugenll O18783 806 90963 E345 T N P D V R Q E Y C A I P S C
Platypus Ornith. anatinus XP_001511876 701 76014 G366 A G R P G A G G L S L G A G G
Chicken Gallus gallus P25155 475 53123 E159 C S C T S G Y E L A E D G K Q
Frog Xenopus laevis NP_001086517 607 69214 S270 E G L W C F V S H P N L T Y D
Zebra Danio Brachydanio rerio NP_998555 524 59542 G208 L D K F V E E G G G R E R T T
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 K279 C Y V N A S G K V I V D Y W D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 Q628 S R V H Q T D Q I I L I S G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 0 93.3 6.6 N.A. 20 13.3 6.6 13.3 0 6.6 0 13.3 N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 93.3 6.6 N.A. 20 13.3 6.6 13.3 13.3 13.3 0 33.3 N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 16 16 0 0 0 8 8 8 8 8 0 % A
% Cys: 16 8 24 8 8 0 0 8 16 8 0 0 0 31 8 % C
% Asp: 0 8 0 8 16 0 8 0 0 24 0 16 8 0 16 % D
% Glu: 8 0 0 0 8 8 16 16 0 0 8 24 0 0 16 % E
% Phe: 8 0 0 16 0 24 8 0 0 0 16 0 0 0 0 % F
% Gly: 16 24 0 24 8 16 24 16 24 16 0 8 8 16 16 % G
% His: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 16 0 16 0 0 0 % I
% Lys: 0 16 8 0 8 0 0 8 8 0 0 8 0 8 8 % K
% Leu: 8 0 8 0 0 0 0 0 16 0 31 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 8 0 0 0 0 0 8 8 16 0 8 8 % N
% Pro: 0 8 24 8 0 0 0 8 8 8 0 0 8 0 0 % P
% Gln: 0 0 0 0 8 8 24 16 0 0 0 0 0 0 8 % Q
% Arg: 0 8 16 0 0 8 0 0 0 8 16 0 16 0 0 % R
% Ser: 8 8 0 0 8 8 0 8 0 8 8 0 8 8 8 % S
% Thr: 8 0 0 8 0 16 8 0 0 0 0 0 8 8 16 % T
% Val: 0 0 16 8 24 0 8 8 8 0 8 0 0 0 0 % V
% Trp: 8 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 8 8 0 0 0 8 16 8 0 0 0 39 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _