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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2
All Species:
27.58
Human Site:
Y600
Identified Species:
50.56
UniProt:
P00734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00734
NP_000497.1
622
70037
Y600
G
C
D
R
D
G
K
Y
G
F
Y
T
H
V
F
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
Y450
I
Y
T
K
V
S
R
Y
V
N
W
I
K
E
K
Rhesus Macaque
Macaca mulatta
NP_001098055
627
70600
Y605
G
C
D
R
D
G
K
Y
G
F
Y
T
H
V
F
Dog
Lupus familis
XP_855946
493
54567
G482
D
R
S
M
K
A
R
G
A
A
P
A
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P19221
618
70250
Y597
G
C
D
R
K
G
K
Y
G
F
Y
T
H
V
F
Rat
Rattus norvegicus
P18292
617
70393
Y596
G
C
D
R
N
G
K
Y
G
F
Y
T
H
V
F
Wallaby
Macropus eugenll
O18783
806
90963
P786
G
C
A
R
P
N
K
P
G
V
Y
V
R
V
S
Platypus
Ornith. anatinus
XP_001511876
701
76014
Y679
G
C
D
R
D
G
K
Y
G
F
Y
T
H
V
F
Chicken
Gallus gallus
P25155
475
53123
F464
V
Y
T
K
L
S
R
F
L
R
W
V
R
T
V
Frog
Xenopus laevis
NP_001086517
607
69214
Y584
G
C
D
R
D
G
K
Y
G
F
Y
V
H
L
H
Zebra Danio
Brachydanio rerio
NP_998555
524
59542
K513
R
M
R
R
W
M
K
K
V
I
E
K
T
D
S
Tiger Blowfish
Takifugu rubipres
NP_001027864
612
69604
Y593
G
C
D
R
D
G
K
Y
G
F
Y
T
H
V
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783851
948
105521
L936
Y
G
Y
Y
T
K
I
L
R
L
H
S
W
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
92.6
32.9
N.A.
81.1
79.9
23.3
44.3
31.1
58.6
50.3
52.8
N.A.
N.A.
N.A.
24.4
Protein Similarity:
100
43.8
95
45.3
N.A.
88.7
88
37.1
54.2
46.7
74.4
64.4
70.7
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
6.6
100
0
N.A.
93.3
93.3
46.6
100
0
80
13.3
100
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
6.6
N.A.
93.3
100
46.6
100
26.6
86.6
13.3
100
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
8
0
8
0
8
0
% A
% Cys:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
54
0
39
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
54
0
0
0
0
47
% F
% Gly:
62
8
0
0
0
54
0
8
62
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
54
0
8
% H
% Ile:
8
0
0
0
0
0
8
0
0
8
0
8
0
8
0
% I
% Lys:
0
0
0
16
16
8
70
8
0
0
0
8
8
0
8
% K
% Leu:
0
0
0
0
8
0
0
8
8
8
0
0
8
8
0
% L
% Met:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
8
70
0
0
24
0
8
8
0
0
16
0
0
% R
% Ser:
0
0
8
0
0
16
0
0
0
0
0
8
0
0
16
% S
% Thr:
0
0
16
0
8
0
0
0
0
0
0
47
8
8
0
% T
% Val:
8
0
0
0
8
0
0
0
16
8
0
24
0
54
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
16
0
8
0
0
% W
% Tyr:
8
16
8
8
0
0
0
62
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _