Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2 All Species: 18.48
Human Site: Y67 Identified Species: 33.89
UniProt: P00734 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00734 NP_000497.1 622 70037 Y67 C V E E T C S Y E E A F E A L
Chimpanzee Pan troglodytes Q95ND7 461 51746
Rhesus Macaque Macaca mulatta NP_001098055 627 70600 Y75 C V E E T C S Y E E A F E A L
Dog Lupus familis XP_855946 493 54567
Cat Felis silvestris
Mouse Mus musculus P19221 618 70250 Y68 C V E E Q C S Y E E A F E A L
Rat Rattus norvegicus P18292 617 70393 Y68 C V E E Q C S Y E E A F E A L
Wallaby Macropus eugenll O18783 806 90963 F64 T E F V C R S F E H Y N K E Q
Platypus Ornith. anatinus XP_001511876 701 76014 Y147 C L E E L C S Y E E A F E A L
Chicken Gallus gallus P25155 475 53123
Frog Xenopus laevis NP_001086517 607 69214 I62 E R E C I E E I C N Y E E L R
Zebra Danio Brachydanio rerio NP_998555 524 59542
Tiger Blowfish Takifugu rubipres NP_001027864 612 69604 Q65 C M E E K C N Q E E A R E V F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783851 948 105521 S138 G I A V D S I S K L V Y W S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 92.6 32.9 N.A. 81.1 79.9 23.3 44.3 31.1 58.6 50.3 52.8 N.A. N.A. N.A. 24.4
Protein Similarity: 100 43.8 95 45.3 N.A. 88.7 88 37.1 54.2 46.7 74.4 64.4 70.7 N.A. N.A. N.A. 37.2
P-Site Identity: 100 0 100 0 N.A. 93.3 93.3 13.3 86.6 0 13.3 0 53.3 N.A. N.A. N.A. 0
P-Site Similarity: 100 0 100 0 N.A. 93.3 93.3 26.6 93.3 0 13.3 0 66.6 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 47 0 0 39 0 % A
% Cys: 47 0 0 8 8 47 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 8 8 54 47 0 8 8 0 54 47 0 8 54 8 0 % E
% Phe: 0 0 8 0 0 0 0 8 0 0 0 39 0 0 8 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 8 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 0 0 0 8 0 0 % K
% Leu: 0 8 0 0 8 0 0 0 0 8 0 0 0 8 39 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 16 0 0 8 0 0 0 0 0 0 8 % Q
% Arg: 0 8 0 0 0 8 0 0 0 0 0 8 0 0 8 % R
% Ser: 0 0 0 0 0 8 47 8 0 0 0 0 0 8 0 % S
% Thr: 8 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 31 0 16 0 0 0 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 39 0 0 16 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _