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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HP
All Species:
20.61
Human Site:
S316
Identified Species:
56.67
UniProt:
P00738
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00738
NP_001119574.1
406
45205
S316
C
I
R
H
Y
E
G
S
T
V
P
E
K
K
T
Chimpanzee
Pan troglodytes
Q28801
346
38849
S256
C
I
R
H
Y
E
G
S
T
V
P
E
K
K
T
Rhesus Macaque
Macaca mulatta
XP_001103863
347
38336
S257
C
I
K
H
Y
E
G
S
T
V
P
E
K
K
T
Dog
Lupus familis
XP_850996
347
38364
S257
C
V
Q
H
Y
E
G
S
T
V
P
E
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61646
347
38734
S257
C
V
V
H
Y
E
N
S
T
V
P
E
K
K
N
Rat
Rattus norvegicus
P06866
347
38545
S257
C
E
L
H
Y
E
K
S
T
V
P
E
K
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416518
712
80488
R621
V
Q
L
P
A
V
S
R
E
K
C
Q
S
W
L
Frog
Xenopus laevis
NP_001086316
476
53264
K387
C
K
T
Y
L
N
K
K
R
P
A
I
R
Y
P
Zebra Danio
Brachydanio rerio
NP_001116330
684
76146
N592
H
L
P
V
S
N
F
N
D
C
K
T
K
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
81
70.6
N.A.
69.2
68.2
N.A.
N.A.
21.6
28.7
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81
83
78
N.A.
77.3
76.8
N.A.
N.A.
33.9
47.9
36.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
73.3
N.A.
N.A.
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
78
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% D
% Glu:
0
12
0
0
0
67
0
0
12
0
0
67
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
12
% G
% His:
12
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
12
12
0
0
0
23
12
0
12
12
0
78
67
0
% K
% Leu:
0
12
23
0
12
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
23
12
12
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
12
0
0
0
0
0
12
67
0
0
0
12
% P
% Gln:
0
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
23
0
0
0
0
12
12
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
12
0
12
67
0
0
0
0
12
0
12
% S
% Thr:
0
0
12
0
0
0
0
0
67
0
0
12
0
0
34
% T
% Val:
12
23
12
12
0
12
0
0
0
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
12
67
0
0
0
0
0
0
0
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _