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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HP All Species: 21.21
Human Site: Y66 Identified Species: 58.33
UniProt: P00738 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00738 NP_001119574.1 406 45205 Y66 R T E G D G V Y T L N D K K Q
Chimpanzee Pan troglodytes Q28801 346 38849 Y65 R T E G D G V Y T L N D K K Q
Rhesus Macaque Macaca mulatta XP_001103863 347 38336 Y66 R T E G D G V Y T L N N E K Q
Dog Lupus familis XP_850996 347 38364 Y66 H T E G D G V Y T L N S E K H
Cat Felis silvestris
Mouse Mus musculus Q61646 347 38734 Y66 R A E G D G V Y T L N D E K Q
Rat Rattus norvegicus P06866 347 38545 Y66 Q T E G D G I Y T L N S E K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416518 712 80488 F241 I L K F L E P F E I D D H Q Q
Frog Xenopus laevis NP_001086316 476 53264 P126 E M D G G I I P Y K G F Q A F
Zebra Danio Brachydanio rerio NP_001116330 684 76146 K243 Q C P Y D I L K I T A G G R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.5 81 70.6 N.A. 69.2 68.2 N.A. N.A. 21.6 28.7 22.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81 83 78 N.A. 77.3 76.8 N.A. N.A. 33.9 47.9 36.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 86.6 73.3 N.A. N.A. 13.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 93.3 93.3 N.A. N.A. 46.6 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 12 0 0 12 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 78 0 0 0 0 0 12 45 0 0 0 % D
% Glu: 12 0 67 0 0 12 0 0 12 0 0 0 45 0 12 % E
% Phe: 0 0 0 12 0 0 0 12 0 0 0 12 0 0 12 % F
% Gly: 0 0 0 78 12 67 0 0 0 0 12 12 12 0 0 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 12 0 12 % H
% Ile: 12 0 0 0 0 23 23 0 12 12 0 0 0 0 0 % I
% Lys: 0 0 12 0 0 0 0 12 0 12 0 0 23 67 0 % K
% Leu: 0 12 0 0 12 0 12 0 0 67 0 0 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 67 12 0 0 0 % N
% Pro: 0 0 12 0 0 0 12 12 0 0 0 0 0 0 0 % P
% Gln: 23 0 0 0 0 0 0 0 0 0 0 0 12 12 67 % Q
% Arg: 45 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % S
% Thr: 0 56 0 0 0 0 0 0 67 12 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 67 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _