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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F9 All Species: 37.58
Human Site: T445 Identified Species: 82.67
UniProt: P00740 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00740 NP_000124.1 461 51778 T445 K G K Y G I Y T K V S R Y V N
Chimpanzee Pan troglodytes Q95ND7 461 51746 T445 K G K Y G I Y T K V S R Y V N
Rhesus Macaque Macaca mulatta NP_001103153 461 51784 T445 K G K Y G I Y T K V S R Y V N
Dog Lupus familis XP_534191 486 53473 T458 K G K Y G I Y T K V T N F L K
Cat Felis silvestris
Mouse Mus musculus P16294 471 52959 T455 K G K Y G I Y T K V S R Y V N
Rat Rattus norvegicus P16296 282 31429 K267 W G E E C A M K G K Y G I Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513556 469 52480 T453 R G K Y G I Y T K V S R F V K
Chicken Gallus gallus Q804X6 471 51786 T455 P G K Y G I Y T K V A K Y V K
Frog Xenopus laevis NP_001092148 461 51281 T445 K E K Y G V Y T K V S R F T D
Zebra Danio Brachydanio rerio NP_001035400 507 56952 T478 E G K Y G I Y T R I S K Y M A
Tiger Blowfish Takifugu rubipres NP_001027784 537 60431 T519 D G K Y G I Y T R V S R Y Y P
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 42.7 N.A. 80.2 49 N.A. 66.5 54.7 55 43.9 40.4 N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98.9 60.2 N.A. 90.6 56.4 N.A. 79.7 71.9 70.9 61.7 57.5 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 100 6.6 N.A. 80 73.3 66.6 60 73.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 100 13.3 N.A. 93.3 86.6 86.6 93.3 80 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 10 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % F
% Gly: 0 91 0 0 91 0 0 0 10 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 82 0 0 0 10 0 0 10 0 0 % I
% Lys: 55 0 91 0 0 0 0 10 73 10 0 19 0 0 28 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 37 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 19 0 0 64 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 73 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 91 0 0 10 0 0 10 10 % T
% Val: 0 0 0 0 0 10 0 0 0 82 0 0 0 55 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 91 0 0 91 0 0 0 10 0 64 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _