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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F10 All Species: 30.61
Human Site: Y108 Identified Species: 67.33
UniProt: P00742 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00742 NP_000495.1 488 54732 Y108 C K D G L G E Y T C T C L E G
Chimpanzee Pan troglodytes Q95ND7 461 51746 C102 D Q C E S N P C L N G G S C K
Rhesus Macaque Macaca mulatta NP_001098054 488 54823 Y108 C R D G L G E Y T C T C L E G
Dog Lupus familis XP_534191 486 53473 Y108 C K D G L L E Y S C I C L E G
Cat Felis silvestris
Mouse Mus musculus O88947 481 53999 Y108 C R D G I G G Y T C T C S E G
Rat Rattus norvegicus Q63207 482 54247 Y108 C R D G L G S Y T C T C T E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121086 469 52177 Y108 C K D G L A E Y T C L C S A G
Chicken Gallus gallus P25155 475 53123 Y108 C K D G L G S Y T C S C L D G
Frog Xenopus laevis NP_001083161 462 52021 Y107 C K D G I N E Y T C F C N P G
Zebra Danio Brachydanio rerio NP_958870 474 53562 Y106 C K D A I G P Y T C F C Q Q G
Tiger Blowfish Takifugu rubipres NP_001027783 475 53756 I107 Y Q G F N C E I V I P Q L C E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.8 93.6 74.8 N.A. 75.1 74.5 N.A. 64.1 54.2 53.4 45.9 43.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.4 96.7 84.8 N.A. 83.8 85 N.A. 76 69.6 68.4 62.5 62.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 80 N.A. 73.3 80 N.A. 73.3 80 66.6 60 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 86.6 N.A. 86.6 86.6 N.A. 73.3 93.3 73.3 73.3 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % A
% Cys: 82 0 10 0 0 10 0 10 0 82 0 82 0 19 0 % C
% Asp: 10 0 82 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 0 55 0 0 0 0 0 0 46 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % F
% Gly: 0 0 10 73 0 55 10 0 0 0 10 10 0 0 82 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 28 0 0 10 0 10 10 0 0 0 0 % I
% Lys: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 55 10 0 0 10 0 10 0 46 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 19 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 19 0 0 0 10 0 0 10 0 % P
% Gln: 0 19 0 0 0 0 0 0 0 0 0 10 10 10 0 % Q
% Arg: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 19 0 10 0 10 0 28 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 73 0 37 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _