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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFD
All Species:
23.03
Human Site:
S226
Identified Species:
56.3
UniProt:
P00746
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00746
NP_001919.2
253
27033
S226
E
G
V
V
T
S
G
S
R
V
C
G
N
R
K
Chimpanzee
Pan troglodytes
XP_512221
253
27033
S226
E
G
V
V
T
S
G
S
R
V
C
G
N
R
K
Rhesus Macaque
Macaca mulatta
XP_001117186
253
27258
S226
E
G
V
V
T
S
G
S
R
V
C
G
N
R
K
Dog
Lupus familis
XP_542213
287
31496
G229
C
G
N
R
K
K
P
G
I
Y
T
R
V
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P03953
259
28038
S227
E
G
V
V
T
W
G
S
R
V
C
G
N
G
K
Rat
Rattus norvegicus
P32038
263
28424
S227
E
A
V
V
T
W
G
S
R
V
C
G
N
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517361
237
25958
S207
E
A
V
V
T
S
G
S
R
V
C
G
N
W
K
Chicken
Gallus gallus
NP_989788
260
28466
K225
K
G
I
T
S
F
G
K
S
P
C
G
D
P
G
Frog
Xenopus laevis
Q63ZK0
263
29212
Y227
V
A
I
V
Q
G
G
Y
R
R
C
G
L
S
K
Zebra Danio
Brachydanio rerio
NP_001018368
249
27242
G221
V
G
I
T
S
N
G
G
K
K
C
G
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.2
59.2
N.A.
64.4
66.1
N.A.
60.8
35.7
45.6
41.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
97.6
70
N.A.
78.3
77.9
N.A.
72.7
56.5
64.6
61.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
80
N.A.
86.6
26.6
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
86.6
53.3
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
90
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
0
0
0
10
90
20
0
0
0
90
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
10
0
10
10
10
0
0
0
0
60
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
60
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
70
10
0
10
0
40
20
% R
% Ser:
0
0
0
0
20
40
0
60
10
0
0
0
10
20
10
% S
% Thr:
0
0
0
20
60
0
0
0
0
0
10
0
0
0
0
% T
% Val:
20
0
60
70
0
0
0
0
0
60
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
20
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _