Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLG All Species: 14.55
Human Site: S477 Identified Species: 32
UniProt: P00747 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00747 NP_000292.1 810 90569 S477 L P D V E T P S E E D C M F G
Chimpanzee Pan troglodytes XP_001152889 810 90414 S477 L P N V E T P S E E D C M F G
Rhesus Macaque Macaca mulatta P12545 810 90237 S477 L P D A E T P S E E D C M F G
Dog Lupus familis XP_533468 812 91151 E477 P Q V P S G Q E P S A S D C M
Cat Felis silvestris
Mouse Mus musculus P20918 812 90763 S477 E P S G P S D S E T D C M Y G
Rat Rattus norvegicus Q01177 812 90517 S477 V P S A P G T S E T D C M Y G
Wallaby Macropus eugenll O18783 806 90963 M477 S H P E S D C M Y G S G K D Y
Platypus Ornith. anatinus XP_001506451 860 97099 P519 L R V V N G I P T R T N V G W
Chicken Gallus gallus XP_419618 802 90746 N477 N P D C I H S N G I D Y R G T
Frog Xenopus laevis NP_001081677 716 81953 L410 E K R N D L E L S L D Q P Y L
Zebra Danio Brachydanio rerio NP_958880 818 91617 S484 A Q S T P D Q S A P S E K D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 92.8 83.2 N.A. 79.1 78.9 69.5 26.3 62.7 37.1 57.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 96.6 90.6 N.A. 86.6 86.6 83.8 41.9 76.4 50.2 70.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 46.6 46.6 0 13.3 20 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 0 N.A. 60 60 0 20 26.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 19 0 0 0 0 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 46 0 10 10 % C
% Asp: 0 0 28 0 10 19 10 0 0 0 64 0 10 19 0 % D
% Glu: 19 0 0 10 28 0 10 10 46 28 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % F
% Gly: 0 0 0 10 0 28 0 0 10 10 0 10 0 19 46 % G
% His: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 19 0 0 % K
% Leu: 37 0 0 0 0 10 0 10 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 46 0 10 % M
% Asn: 10 0 10 10 10 0 0 10 0 0 0 10 0 0 0 % N
% Pro: 10 55 10 10 28 0 28 10 10 10 0 0 10 0 0 % P
% Gln: 0 19 0 0 0 0 19 0 0 0 0 10 0 0 0 % Q
% Arg: 0 10 10 0 0 0 0 0 0 10 0 0 10 0 0 % R
% Ser: 10 0 28 0 19 10 10 55 10 10 19 10 0 0 0 % S
% Thr: 0 0 0 10 0 28 10 0 10 19 10 0 0 0 10 % T
% Val: 10 0 19 28 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 10 0 28 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _