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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFB
All Species:
14.85
Human Site:
S284
Identified Species:
40.83
UniProt:
P00751
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00751
NP_001701.2
764
85533
S284
G
S
D
S
I
G
A
S
N
F
T
G
A
K
K
Chimpanzee
Pan troglodytes
Q864W0
764
85494
S284
G
S
D
S
I
G
A
S
N
F
T
G
A
K
K
Rhesus Macaque
Macaca mulatta
XP_001113705
763
85518
G284
G
S
D
S
I
G
A
G
N
F
T
G
A
K
K
Dog
Lupus familis
XP_532086
767
86303
G284
G
S
D
S
I
G
A
G
N
F
T
R
A
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P04186
761
84986
S281
G
S
D
S
I
G
S
S
N
F
T
G
A
K
R
Rat
Rattus norvegicus
NP_997631
763
85335
S283
G
S
D
S
I
G
A
S
N
F
T
G
A
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518715
697
76676
P271
P
K
A
S
P
T
A
P
I
T
R
G
V
S
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081234
747
85150
S272
I
L
F
I
E
K
M
S
N
Y
D
I
K
P
R
Zebra Danio
Brachydanio rerio
NP_001077327
751
84299
E268
S
I
D
E
E
D
F
E
R
A
K
D
V
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.7
81
N.A.
83.9
84.2
N.A.
30.8
N.A.
42.4
39.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
97.6
90.7
N.A.
91.8
92.4
N.A.
47.5
N.A.
61.3
59.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
93.3
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
100
100
N.A.
20
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
67
0
0
12
0
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
78
0
0
12
0
0
0
0
12
12
0
0
0
% D
% Glu:
0
0
0
12
23
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
12
0
0
67
0
0
0
0
0
% F
% Gly:
67
0
0
0
0
67
0
23
0
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
12
67
0
0
0
12
0
0
12
0
12
0
% I
% Lys:
0
12
0
0
0
12
0
0
0
0
12
0
12
67
45
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
12
% N
% Pro:
12
0
0
0
12
0
0
12
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
12
12
0
0
34
% R
% Ser:
12
67
0
78
0
0
12
56
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
12
67
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _