Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CFB All Species: 9.7
Human Site: T92 Identified Species: 26.67
UniProt: P00751 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00751 NP_001701.2 764 85533 T92 L K T Q D Q K T V R K A E C R
Chimpanzee Pan troglodytes Q864W0 764 85494 T92 L K T Q V Q K T V R K A E C R
Rhesus Macaque Macaca mulatta XP_001113705 763 85518 T92 L Q T Q D R K T V K K A E C R
Dog Lupus familis XP_532086 767 86303 V92 L Q T Q D K M V V K K A E C R
Cat Felis silvestris
Mouse Mus musculus P04186 761 84986 E94 Q K I V Q K A E C R A I R C P
Rat Rattus norvegicus NP_997631 763 85335 E96 Q K I V K K A E C R A I R C P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518715 697 76676 T93 N P V G T T R T G S R F T A G
Chicken Gallus gallus
Frog Xenopus laevis NP_001081234 747 85150 R94 E D G D Y E P R Q P F Y K V G
Zebra Danio Brachydanio rerio NP_001077327 751 84299 A92 I T C P D P R A F L N G D V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 94.7 81 N.A. 83.9 84.2 N.A. 30.8 N.A. 42.4 39.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 97.6 90.7 N.A. 91.8 92.4 N.A. 47.5 N.A. 61.3 59.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 80 66.6 N.A. 20 20 N.A. 6.6 N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 86.6 N.A. 26.6 26.6 N.A. 20 N.A. 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 23 12 0 0 23 45 0 12 0 % A
% Cys: 0 0 12 0 0 0 0 0 23 0 0 0 0 67 0 % C
% Asp: 0 12 0 12 45 0 0 0 0 0 0 0 12 0 0 % D
% Glu: 12 0 0 0 0 12 0 23 0 0 0 0 45 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 12 12 0 0 0 % F
% Gly: 0 0 12 12 0 0 0 0 12 0 0 12 0 0 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 12 0 23 0 0 0 0 0 0 0 0 23 0 0 0 % I
% Lys: 0 45 0 0 12 34 34 0 0 23 45 0 12 0 0 % K
% Leu: 45 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 12 0 12 0 12 12 0 0 12 0 0 0 0 23 % P
% Gln: 23 23 0 45 12 23 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 12 23 12 0 45 12 0 23 0 45 % R
% Ser: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % S
% Thr: 0 12 45 0 12 12 0 45 0 0 0 0 12 0 0 % T
% Val: 0 0 12 23 12 0 0 12 45 0 0 0 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _