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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REN
All Species:
6.36
Human Site:
Y228
Identified Species:
14
UniProt:
P00797
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00797
NP_000528.1
406
45057
Y228
E
D
V
F
S
F
Y
Y
N
R
D
S
E
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q6DLW5
406
44943
Y228
E
D
V
F
S
F
Y
Y
N
R
D
S
E
N
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P06281
402
44324
S223
V
L
K
E
E
V
F
S
V
Y
Y
N
R
G
S
Rat
Rattus norvegicus
P08424
402
44257
S223
V
L
K
E
E
V
F
S
V
Y
Y
S
R
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520972
377
41471
V207
N
S
K
N
D
H
M
V
P
G
G
E
I
I
L
Chicken
Gallus gallus
Q05744
398
43280
F219
I
E
K
N
I
F
S
F
Y
L
N
R
D
P
T
Frog
Xenopus laevis
Q805F3
397
42889
V213
V
E
L
P
M
F
S
V
Y
M
S
R
N
P
N
Zebra Danio
Brachydanio rerio
NP_998025
395
43019
V216
L
K
E
N
V
F
S
V
Y
Y
S
R
D
P
T
Tiger Blowfish
Takifugu rubipres
NP_001072054
396
43175
I218
L
K
E
E
V
F
S
I
Y
Y
S
R
D
P
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392857
385
42204
F206
V
P
Q
P
V
F
S
F
Y
L
N
R
N
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q01294
396
42914
V221
Q
K
L
V
D
E
P
V
F
S
F
Y
L
A
D
Conservation
Percent
Protein Identity:
100
N.A.
98.7
N.A.
N.A.
69.9
66.7
N.A.
49.2
44
40.1
50.7
48.2
N.A.
40.8
N.A.
N.A.
Protein Similarity:
100
N.A.
99.2
N.A.
N.A.
82.2
81.2
N.A.
67.9
62.5
58.6
67.9
66.7
N.A.
60
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
N.A.
N.A.
6.6
13.3
N.A.
0
6.6
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
20
20
N.A.
0
40
26.6
20
13.3
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
19
0
0
0
0
0
19
0
28
0
19
% D
% Glu:
19
19
19
28
19
10
0
0
0
0
0
10
19
10
0
% E
% Phe:
0
0
0
19
0
64
19
19
10
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
10
0
0
0
0
10
10
0
% I
% Lys:
0
28
37
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
19
19
19
0
0
0
0
0
0
19
0
0
10
0
10
% L
% Met:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
28
0
0
0
0
19
0
19
10
19
19
10
% N
% Pro:
0
10
0
19
0
0
10
0
10
0
0
0
0
46
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
19
0
46
19
0
0
% R
% Ser:
0
10
0
0
19
0
46
19
0
10
28
28
0
0
28
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% T
% Val:
37
0
19
10
28
19
0
37
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
19
46
37
19
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _