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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADA
All Species:
13.64
Human Site:
S291
Identified Species:
27.27
UniProt:
P00813
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00813
NP_000013.2
363
40764
S291
K
N
D
Q
A
N
Y
S
L
N
T
D
D
P
L
Chimpanzee
Pan troglodytes
XP_001144517
363
40678
S291
K
N
D
Q
A
N
Y
S
L
N
T
D
D
P
L
Rhesus Macaque
Macaca mulatta
XP_001109908
572
62188
S500
K
N
D
Q
A
N
Y
S
L
N
T
D
D
P
L
Dog
Lupus familis
XP_534428
362
41003
S290
K
N
D
Q
A
N
Y
S
L
N
T
D
D
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P03958
352
39973
V281
P
K
T
T
H
A
V
V
R
F
K
N
D
K
A
Rat
Rattus norvegicus
Q920P6
352
39881
V281
P
K
T
T
H
A
V
V
R
F
K
D
D
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508594
308
34510
L237
V
L
P
A
V
D
V
L
K
A
E
R
I
G
H
Chicken
Gallus gallus
Q5ZKP6
357
40660
K284
H
P
V
V
Q
F
K
K
D
Q
A
N
Y
S
I
Frog
Xenopus laevis
Q6GP70
358
40658
A287
T
Q
F
R
K
D
K
A
N
F
S
L
N
T
D
Zebra Danio
Brachydanio rerio
Q6DG22
359
40825
A288
I
T
F
K
K
D
K
A
N
Y
S
L
N
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501087
391
43657
L309
V
M
T
G
A
V
P
L
D
W
K
N
H
P
I
Sea Urchin
Strong. purpuratus
XP_785367
391
43729
R320
L
S
D
H
I
A
K
R
F
A
K
D
G
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
61.3
85.6
N.A.
80.9
83.1
N.A.
58.9
65.5
69.1
64.1
N.A.
N.A.
N.A.
31.4
35.8
Protein Similarity:
100
99.4
62.7
91.4
N.A.
90.6
91.4
N.A.
68.3
79
81.8
78.5
N.A.
N.A.
N.A.
50.3
54.4
P-Site Identity:
100
100
100
100
N.A.
6.6
13.3
N.A.
0
0
0
0
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
6.6
13.3
33.3
33.3
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
42
25
0
17
0
17
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
0
0
25
0
0
17
0
0
50
50
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
17
0
0
9
0
0
9
25
0
0
0
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
9
9
0
% G
% His:
9
0
0
9
17
0
0
0
0
0
0
0
9
0
9
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
0
9
0
17
% I
% Lys:
34
17
0
9
17
0
34
9
9
0
34
0
0
9
0
% K
% Leu:
9
9
0
0
0
0
0
17
34
0
0
17
0
0
34
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
0
34
0
0
17
34
0
25
17
0
9
% N
% Pro:
17
9
9
0
0
0
9
0
0
0
0
0
0
42
0
% P
% Gln:
0
9
0
34
9
0
0
0
0
9
0
0
0
9
0
% Q
% Arg:
0
0
0
9
0
0
0
9
17
0
0
9
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
34
0
0
17
0
0
9
0
% S
% Thr:
9
9
25
17
0
0
0
0
0
0
34
0
0
17
0
% T
% Val:
17
0
9
9
9
9
25
17
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _