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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADA All Species: 14.55
Human Site: Y308 Identified Species: 29.09
UniProt: P00813 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00813 NP_000013.2 363 40764 Y308 K S T L D T D Y Q M T K R D M
Chimpanzee Pan troglodytes XP_001144517 363 40678 Y308 K S T L D T D Y Q M T K R D M
Rhesus Macaque Macaca mulatta XP_001109908 572 62188 Y517 K S T L D T D Y Q M T K R D M
Dog Lupus familis XP_534428 362 41003 Y307 K S T L E T D Y Q M T K Q G M
Cat Felis silvestris
Mouse Mus musculus P03958 352 39973 L298 S L N T D D P L I F K S T L D
Rat Rattus norvegicus Q920P6 352 39881 L298 S L N S D D P L I F K S T V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508594 308 34510 L254 H T L E D P A L Y S R L K A E
Chicken Gallus gallus Q5ZKP6 357 40660 S301 D D P L I F N S N I D K D Y G
Frog Xenopus laevis Q6GP70 358 40658 D304 L I F G S T L D V D Y S I A V
Zebra Danio Brachydanio rerio Q6DG22 359 40825 N305 T I F N S T L N S D Y E V V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501087 391 43657 F326 W A K D D V N F S V S R D D P
Sea Urchin Strong. purpuratus XP_785367 391 43729 L337 I N T D D P T L L L N T M E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 61.3 85.6 N.A. 80.9 83.1 N.A. 58.9 65.5 69.1 64.1 N.A. N.A. N.A. 31.4 35.8
Protein Similarity: 100 99.4 62.7 91.4 N.A. 90.6 91.4 N.A. 68.3 79 81.8 78.5 N.A. N.A. N.A. 50.3 54.4
P-Site Identity: 100 100 100 80 N.A. 6.6 6.6 N.A. 6.6 13.3 6.6 6.6 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. 20 26.6 13.3 13.3 N.A. N.A. N.A. 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 9 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 17 67 17 34 9 0 17 9 0 17 34 17 % D
% Glu: 0 0 0 9 9 0 0 0 0 0 0 9 0 9 9 % E
% Phe: 0 0 17 0 0 9 0 9 0 17 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 9 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 17 0 0 9 0 0 0 17 9 0 0 9 0 0 % I
% Lys: 34 0 9 0 0 0 0 0 0 0 17 42 9 0 0 % K
% Leu: 9 17 9 42 0 0 17 34 9 9 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 34 0 0 9 0 34 % M
% Asn: 0 9 17 9 0 0 17 9 9 0 9 0 0 0 0 % N
% Pro: 0 0 9 0 0 17 17 0 0 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 34 0 0 0 9 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 9 25 0 0 % R
% Ser: 17 34 0 9 17 0 0 9 17 9 9 25 0 0 9 % S
% Thr: 9 9 42 9 0 50 9 0 0 0 34 9 17 0 0 % T
% Val: 0 0 0 0 0 9 0 0 9 9 0 0 9 17 9 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 9 0 17 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _