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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADA All Species: 21.82
Human Site: Y67 Identified Species: 43.64
UniProt: P00813 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00813 NP_000013.2 363 40764 Y67 D F L A K F D Y Y M P A I A G
Chimpanzee Pan troglodytes XP_001144517 363 40678 Y67 D F L A K F D Y Y M P A I A G
Rhesus Macaque Macaca mulatta XP_001109908 572 62188 Y276 E F L A K F D Y Y M P A I A G
Dog Lupus familis XP_534428 362 41003 Y67 S F L A K F N Y Y M P A I A G
Cat Felis silvestris
Mouse Mus musculus P03958 352 39973 Y67 G F L A K F D Y Y M P V I A G
Rat Rattus norvegicus Q920P6 352 39881 Y67 D F L A K F D Y Y M P A I A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508594 308 34510 G25 E L H V H L D G A I K P E T I
Chicken Gallus gallus Q5ZKP6 357 40660 H68 L F L E K F N H Y M P A I A G
Frog Xenopus laevis Q6GP70 358 40658 H66 E F L Q K F N H Y M P A I A G
Zebra Danio Brachydanio rerio Q6DG22 359 40825 H67 E F L G K F S H F M H V I A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501087 391 43657 D65 L D G A V R F D T L I D L S Q
Sea Urchin Strong. purpuratus XP_785367 391 43729 I105 F L S S F D R I L P I I A G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 61.3 85.6 N.A. 80.9 83.1 N.A. 58.9 65.5 69.1 64.1 N.A. N.A. N.A. 31.4 35.8
Protein Similarity: 100 99.4 62.7 91.4 N.A. 90.6 91.4 N.A. 68.3 79 81.8 78.5 N.A. N.A. N.A. 50.3 54.4
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 100 N.A. 6.6 73.3 73.3 53.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 100 N.A. 20 86.6 93.3 73.3 N.A. N.A. N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 59 0 0 0 0 9 0 0 59 9 75 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 9 0 0 0 9 50 9 0 0 0 9 0 0 9 % D
% Glu: 34 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 9 75 0 0 9 75 9 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 9 9 0 0 0 9 0 0 0 0 0 9 75 % G
% His: 0 0 9 0 9 0 0 25 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 9 17 9 75 0 9 % I
% Lys: 0 0 0 0 75 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 17 17 75 0 0 9 0 0 9 9 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 67 9 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 9 9 0 0 9 0 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % T
% Val: 0 0 0 9 9 0 0 0 0 0 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _