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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASS1 All Species: 33.64
Human Site: S368 Identified Species: 67.27
UniProt: P00966 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00966 NP_000041.2 412 46530 S368 L G R E S P L S L Y N E E L V
Chimpanzee Pan troglodytes XP_001165570 452 50783 S408 L G R E S P L S L Y N E E L V
Rhesus Macaque Macaca mulatta XP_001095864 412 46267 S368 L S R E S P L S L Y N E E L V
Dog Lupus familis XP_849895 412 46588 S368 L S R E S P L S L Y N E E L V
Cat Felis silvestris
Mouse Mus musculus P16460 412 46566 S368 L G R E S P L S L Y N E E L V
Rat Rattus norvegicus P09034 412 46478 S368 L G R E S P L S L Y N E E L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ23 416 46885 S369 L G R E S P H S L Y N E E L V
Frog Xenopus laevis Q7ZWM4 411 46731 P367 Y V L G R E A P H S L Y N E E
Zebra Danio Brachydanio rerio Q66I24 414 47110 S367 L G R E S P K S L Y N E E L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97069 419 46576 A371 K A A K D V G A L Y N E Q L V
Honey Bee Apis mellifera XP_396374 412 46903 S369 L S R H S K T S L Y N Q S L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22768 420 46921 E372 L G R S T K T E K L Y D P T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.7 97.3 98 N.A. 96.8 97.5 N.A. N.A. 78.1 81.3 76.5 N.A. 53.9 58 N.A. N.A.
Protein Similarity: 100 90.9 98.3 99.2 N.A. 98.7 99 N.A. N.A. 89.9 91.5 88.8 N.A. 71.5 73.5 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 100 100 N.A. N.A. 93.3 0 93.3 N.A. 40 60 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 100 100 N.A. N.A. 93.3 0 93.3 N.A. 60 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 69 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 9 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 67 0 9 0 9 0 0 0 75 67 9 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 59 0 9 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 9 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 9 0 17 9 0 9 0 0 0 0 0 0 % K
% Leu: 84 0 9 0 0 0 50 0 84 9 9 0 0 84 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 84 0 9 0 0 % N
% Pro: 0 0 0 0 0 67 0 9 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % Q
% Arg: 0 0 84 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 25 0 9 75 0 0 75 0 9 0 0 9 0 0 % S
% Thr: 0 0 0 0 9 0 17 0 0 0 0 0 0 9 0 % T
% Val: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 84 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 84 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _