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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINK1
All Species:
22.73
Human Site:
Y43
Identified Species:
62.5
UniProt:
P00995
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00995
NP_003113.2
79
8507
Y43
L
N
G
C
T
K
I
Y
D
P
V
C
G
T
D
Chimpanzee
Pan troglodytes
XP_001160275
79
8502
Y43
L
N
G
C
T
K
I
Y
D
P
V
C
G
T
D
Rhesus Macaque
Macaca mulatta
XP_001102888
79
8475
Y43
L
T
G
C
T
K
I
Y
D
P
V
C
G
T
D
Dog
Lupus familis
XP_850557
80
8676
Y44
V
N
G
C
N
K
I
Y
N
P
I
C
G
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P09036
80
8469
Y44
V
A
G
C
P
R
I
Y
D
P
V
C
G
T
D
Rat
Rattus norvegicus
P09656
79
8547
Y43
L
V
G
C
P
R
D
Y
D
P
V
C
G
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516941
64
6857
E29
G
A
L
G
E
G
R
E
P
N
C
K
T
P
L
Chicken
Gallus gallus
P85000
55
6014
S20
P
G
C
P
R
D
Y
S
P
V
C
G
T
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664355
80
8618
Y44
S
Q
A
C
P
L
N
Y
S
P
V
C
G
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.6
70
N.A.
68.7
67
N.A.
43
39.2
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.4
86.2
N.A.
78.7
77.2
N.A.
53.1
45.5
N.A.
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
73.3
73.3
N.A.
0
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
0
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
78
0
0
0
0
0
0
23
78
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
56
0
0
0
0
12
78
% D
% Glu:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
67
12
0
12
0
0
0
0
0
12
78
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
56
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
45
0
0
0
0
0
12
0
0
0
% K
% Leu:
45
0
12
0
0
12
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
12
0
12
0
12
12
0
0
0
12
0
% N
% Pro:
12
0
0
12
34
0
0
0
23
78
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
23
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
12
12
0
0
0
0
12
0
% S
% Thr:
0
12
0
0
34
0
0
0
0
0
0
0
23
56
0
% T
% Val:
23
12
0
0
0
0
0
0
0
12
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _