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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINC1
All Species:
22.12
Human Site:
S194
Identified Species:
48.67
UniProt:
P01008
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01008
NP_000479.1
464
52602
S194
N
E
T
Y
Q
D
I
S
E
L
V
Y
G
A
K
Chimpanzee
Pan troglodytes
XP_001151521
464
52642
S194
N
E
T
Y
Q
D
I
S
E
L
V
Y
G
A
K
Rhesus Macaque
Macaca mulatta
NP_001098053
464
52457
S194
N
E
T
Y
Q
D
I
S
E
L
V
Y
G
A
K
Dog
Lupus familis
XP_850479
471
53158
S195
N
E
T
Y
Q
D
I
S
E
A
V
Y
G
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P32261
465
51985
S195
N
E
S
Y
Q
D
V
S
E
V
V
Y
G
A
K
Rat
Rattus norvegicus
Q4G075
379
42708
Q134
D
A
R
K
E
I
N
Q
W
V
K
G
Q
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515268
523
57961
S256
N
E
T
Y
Q
D
I
S
E
M
L
Y
R
A
K
Chicken
Gallus gallus
Q90935
410
46511
D165
H
T
N
N
M
I
K
D
F
V
S
S
R
D
F
Frog
Xenopus laevis
Q52L45
377
42679
E132
A
L
E
D
A
R
K
E
I
N
K
W
V
S
E
Zebra Danio
Brachydanio rerio
NP_878283
450
50835
P194
P
L
D
F
K
E
K
P
E
A
S
R
I
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787959
393
44064
D147
I
A
T
K
S
I
N
D
W
V
S
K
Q
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
85.3
N.A.
87.3
32.9
N.A.
64.8
31.8
32.5
57.1
N.A.
N.A.
N.A.
N.A.
35.7
Protein Similarity:
100
99.5
97.8
91.5
N.A.
92
51.9
N.A.
75.9
51
49.3
72.4
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
80
0
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
93.3
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
10
0
0
0
0
19
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
0
55
0
19
0
0
0
0
0
10
0
% D
% Glu:
0
55
10
0
10
10
0
10
64
0
0
0
0
0
28
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
46
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
28
46
0
10
0
0
0
10
0
10
% I
% Lys:
0
0
0
19
10
0
28
0
0
0
19
10
0
0
55
% K
% Leu:
0
19
0
0
0
0
0
0
0
28
10
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
55
0
10
10
0
0
19
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
55
0
0
10
0
0
0
0
19
0
0
% Q
% Arg:
0
0
10
0
0
10
0
0
0
0
0
10
19
0
0
% R
% Ser:
0
0
10
0
10
0
0
55
0
0
28
10
0
10
0
% S
% Thr:
0
10
55
0
0
0
0
0
0
0
0
0
0
28
0
% T
% Val:
0
0
0
0
0
0
10
0
0
37
46
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
19
0
0
10
0
0
0
% W
% Tyr:
0
0
0
55
0
0
0
0
0
0
0
55
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _