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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINC1
All Species:
14.55
Human Site:
S377
Identified Species:
32
UniProt:
P01008
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01008
NP_000479.1
464
52602
S377
M
G
L
V
D
L
F
S
P
E
K
S
K
L
P
Chimpanzee
Pan troglodytes
XP_001151521
464
52642
S377
M
G
L
V
D
L
F
S
P
E
K
S
K
L
P
Rhesus Macaque
Macaca mulatta
NP_001098053
464
52457
S377
M
G
L
V
D
L
F
S
P
E
K
S
K
L
P
Dog
Lupus familis
XP_850479
471
53158
L384
F
N
P
E
K
S
R
L
P
G
E
P
R
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P32261
465
51985
S378
M
G
L
I
D
L
F
S
P
E
K
S
Q
L
P
Rat
Rattus norvegicus
Q4G075
379
42708
K301
Q
D
L
F
N
S
S
K
A
D
L
S
G
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515268
523
57961
D438
M
G
L
V
D
L
F
D
P
D
K
A
R
L
P
Chicken
Gallus gallus
Q90935
410
46511
Y332
M
S
D
N
K
E
L
Y
L
A
K
A
F
H
K
Frog
Xenopus laevis
Q52L45
377
42679
G299
M
V
D
L
F
N
S
G
S
A
D
L
S
G
M
Zebra Danio
Brachydanio rerio
NP_878283
450
50835
P362
G
L
E
D
L
F
S
P
A
N
A
S
L
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787959
393
44064
I315
D
R
A
N
F
E
G
I
S
G
D
R
E
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
85.3
N.A.
87.3
32.9
N.A.
64.8
31.8
32.5
57.1
N.A.
N.A.
N.A.
N.A.
35.7
Protein Similarity:
100
99.5
97.8
91.5
N.A.
92
51.9
N.A.
75.9
51
49.3
72.4
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
100
100
100
6.6
N.A.
86.6
13.3
N.A.
73.3
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
33.3
N.A.
93.3
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
19
19
10
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
19
10
46
0
0
10
0
19
19
0
0
0
10
% D
% Glu:
0
0
10
10
0
19
0
0
0
37
10
0
10
0
0
% E
% Phe:
10
0
0
10
19
10
46
0
0
0
0
0
10
0
0
% F
% Gly:
10
46
0
0
0
0
10
10
0
19
0
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
19
0
0
10
0
0
55
0
28
10
10
% K
% Leu:
0
10
55
10
10
46
10
10
10
0
10
10
10
55
0
% L
% Met:
64
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
10
0
19
10
10
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
55
0
0
10
0
10
46
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
0
0
0
0
10
0
0
0
0
10
19
0
0
% R
% Ser:
0
10
0
0
0
19
28
37
19
0
0
55
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
37
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _