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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINC1
All Species:
16.97
Human Site:
Y395
Identified Species:
37.33
UniProt:
P01008
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01008
NP_000479.1
464
52602
Y395
A
E
G
R
D
D
L
Y
V
S
D
A
F
H
K
Chimpanzee
Pan troglodytes
XP_001151521
464
52642
Y395
A
E
G
R
D
D
L
Y
V
S
D
A
F
H
K
Rhesus Macaque
Macaca mulatta
NP_001098053
464
52457
Y395
A
E
G
R
D
D
L
Y
V
S
D
A
F
H
K
Dog
Lupus familis
XP_850479
471
53158
F402
Q
K
A
G
N
D
L
F
V
S
D
A
F
H
K
Cat
Felis silvestris
Mouse
Mus musculus
P32261
465
51985
Y396
A
G
G
R
D
D
L
Y
V
S
D
A
F
H
K
Rat
Rattus norvegicus
Q4G075
379
42708
V319
D
L
F
I
S
K
I
V
H
K
A
F
V
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515268
523
57961
S456
A
G
G
R
S
D
L
S
V
S
E
A
F
H
K
Chicken
Gallus gallus
Q90935
410
46511
E350
E
V
N
E
E
G
S
E
A
A
A
A
S
G
M
Frog
Xenopus laevis
Q52L45
377
42679
V317
N
N
L
F
L
S
E
V
I
H
K
S
F
V
E
Zebra Danio
Brachydanio rerio
NP_878283
450
50835
F380
D
A
E
G
P
N
L
F
I
S
D
A
Y
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787959
393
44064
D333
V
I
H
K
A
F
V
D
V
N
E
E
G
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
85.3
N.A.
87.3
32.9
N.A.
64.8
31.8
32.5
57.1
N.A.
N.A.
N.A.
N.A.
35.7
Protein Similarity:
100
99.5
97.8
91.5
N.A.
92
51.9
N.A.
75.9
51
49.3
72.4
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
100
100
100
60
N.A.
93.3
0
N.A.
73.3
6.6
6.6
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
93.3
6.6
N.A.
80
20
26.6
66.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
10
10
0
10
0
0
0
10
10
19
73
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
37
55
0
10
0
0
55
0
0
0
0
% D
% Glu:
10
28
10
10
10
0
10
10
0
0
19
10
0
10
19
% E
% Phe:
0
0
10
10
0
10
0
19
0
0
0
10
64
0
0
% F
% Gly:
0
19
46
19
0
10
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
10
0
0
0
0
0
10
10
0
0
0
64
0
% H
% Ile:
0
10
0
10
0
0
10
0
19
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
10
0
0
0
10
10
0
0
0
64
% K
% Leu:
0
10
10
0
10
0
64
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
10
10
0
10
10
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
10
10
10
0
64
0
10
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
10
19
64
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _