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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C5 All Species: 11.21
Human Site: S880 Identified Species: 35.24
UniProt: P01031 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01031 NP_001726.2 1676 188305 S880 I D H Q G T K S S K C V R Q K
Chimpanzee Pan troglodytes XP_520228 1676 188121 S880 I D H Q G T K S S K C V R Q K
Rhesus Macaque Macaca mulatta XP_001095750 1678 188833 S880 I D H Q G T K S S K C V R Q K
Dog Lupus familis XP_532046 1197 132609 Y448 E N Q A S K D Y Q A I A Y S S
Cat Felis silvestris
Mouse Mus musculus P06684 1680 188860 P884 A S L H T S R P S R C V F Q R
Rat Rattus norvegicus P01026 1663 186442 Y883 A T A K K R Y Y Q T I E I P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505969 1653 185840 Q877 S T S K K K F Q Q V V E I P A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694622 1697 190715 T864 N K V E G L C T A G G N D V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 94.2 50.4 N.A. 77.8 29.1 N.A. 29.9 N.A. N.A. 29 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 97.1 58.4 N.A. 89.1 49.5 N.A. 50.5 N.A. N.A. 49.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 26.6 0 N.A. 0 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 53.3 6.6 N.A. 6.6 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 13 13 0 0 0 0 13 13 0 13 0 0 13 % A
% Cys: 0 0 0 0 0 0 13 0 0 0 50 0 0 0 0 % C
% Asp: 0 38 0 0 0 0 13 0 0 0 0 0 13 0 0 % D
% Glu: 13 0 0 13 0 0 0 0 0 0 0 25 0 0 0 % E
% Phe: 0 0 0 0 0 0 13 0 0 0 0 0 13 0 0 % F
% Gly: 0 0 0 0 50 0 0 0 0 13 13 0 0 0 0 % G
% His: 0 0 38 13 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 38 0 0 0 0 0 0 0 0 0 25 0 25 0 0 % I
% Lys: 0 13 0 25 25 25 38 0 0 38 0 0 0 0 50 % K
% Leu: 0 0 13 0 0 13 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 13 0 0 0 0 0 0 0 0 0 13 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 13 0 0 0 0 0 25 13 % P
% Gln: 0 0 13 38 0 0 0 13 38 0 0 0 0 50 0 % Q
% Arg: 0 0 0 0 0 13 13 0 0 13 0 0 38 0 13 % R
% Ser: 13 13 13 0 13 13 0 38 50 0 0 0 0 13 13 % S
% Thr: 0 25 0 0 13 38 0 13 0 13 0 0 0 0 0 % T
% Val: 0 0 13 0 0 0 0 0 0 13 13 50 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 25 0 0 0 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _