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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C5
All Species:
16.67
Human Site:
Y499
Identified Species:
52.38
UniProt:
P01031
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01031
NP_001726.2
1676
188305
Y499
Y
I
D
K
I
T
H
Y
N
Y
L
I
L
S
K
Chimpanzee
Pan troglodytes
XP_520228
1676
188121
Y499
Y
I
D
K
I
T
H
Y
N
Y
L
I
L
S
K
Rhesus Macaque
Macaca mulatta
XP_001095750
1678
188833
Y499
Y
I
D
K
I
T
H
Y
N
Y
L
I
L
S
K
Dog
Lupus familis
XP_532046
1197
132609
G91
Q
P
K
Q
L
S
G
G
Q
G
P
V
S
H
V
Cat
Felis silvestris
Mouse
Mus musculus
P06684
1680
188860
Y499
Y
I
D
K
I
T
H
Y
N
Y
L
I
L
S
K
Rat
Rattus norvegicus
P01026
1663
186442
Y489
Q
E
A
K
I
R
Y
Y
T
Y
L
V
M
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505969
1653
185840
A501
I
L
K
A
G
R
Q
A
R
Q
V
G
Q
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694622
1697
190715
Q499
F
M
V
W
S
K
G
Q
I
V
Q
M
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.2
50.4
N.A.
77.8
29.1
N.A.
29.9
N.A.
N.A.
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.1
58.4
N.A.
89.1
49.5
N.A.
50.5
N.A.
N.A.
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
40
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
66.6
N.A.
13.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
13
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
25
13
0
13
0
13
13
0
0
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
0
0
13
0
% H
% Ile:
13
50
0
0
63
0
0
0
13
0
0
50
0
0
0
% I
% Lys:
0
0
25
63
0
13
0
0
0
0
0
0
0
0
63
% K
% Leu:
0
13
0
0
13
0
0
0
0
0
63
0
50
0
13
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
13
13
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
50
0
0
0
0
13
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
25
0
0
13
0
0
13
13
13
13
13
0
13
0
0
% Q
% Arg:
0
0
0
0
0
25
0
0
13
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
13
13
0
0
0
0
0
0
13
50
0
% S
% Thr:
0
0
0
0
0
50
0
0
13
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
13
13
25
0
0
25
% V
% Trp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
13
63
0
63
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _