KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMP1
All Species:
13.33
Human Site:
T49
Identified Species:
29.33
UniProt:
P01033
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01033
NP_003245.1
207
23171
T49
I
R
A
K
F
V
G
T
P
E
V
N
Q
T
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q95KL9
207
23229
T49
I
R
A
K
F
V
G
T
P
E
V
N
Q
T
T
Dog
Lupus familis
XP_538410
211
24134
G48
V
I
R
A
K
V
V
G
K
K
L
V
K
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P12032
205
22610
S50
I
R
A
K
F
M
G
S
P
E
I
N
E
T
T
Rat
Rattus norvegicus
P30120
217
23775
S49
I
R
A
K
F
M
G
S
P
E
I
I
E
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505385
182
20306
H28
G
Q
N
D
S
L
Q
H
H
R
Q
Y
E
I
K
Chicken
Gallus gallus
O42146
220
24294
A52
I
R
A
K
R
V
S
A
K
E
V
D
S
G
N
Frog
Xenopus laevis
O73746
214
24437
K52
I
R
A
K
V
V
G
K
K
L
M
K
D
G
P
Zebra Danio
Brachydanio rerio
NP_878294
220
24449
K51
I
R
A
K
V
V
G
K
K
E
V
D
S
G
N
Tiger Blowfish
Takifugu rubipres
NP_001033040
220
24546
E52
I
R
A
K
V
V
G
E
K
E
V
N
S
G
N
Fruit Fly
Dros. melanogaster
Q9VH14
210
23961
K53
V
Q
L
R
V
L
R
K
S
D
T
I
E
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
39.3
N.A.
72.4
68.6
N.A.
40.5
39
36.9
32.7
35
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.5
57.3
N.A.
85
80.6
N.A.
59.4
53.6
55.1
52.7
55
45.7
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
73.3
66.6
N.A.
0
46.6
40
53.3
60
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
93.3
N.A.
20
53.3
46.6
60
60
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
73
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
19
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
64
0
0
37
10
0
% E
% Phe:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
64
10
0
0
0
0
0
37
19
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
73
10
0
0
0
0
0
0
0
0
19
19
0
10
0
% I
% Lys:
0
0
0
73
10
0
0
28
46
10
0
10
10
0
10
% K
% Leu:
0
0
10
0
0
19
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
19
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
37
0
0
28
% N
% Pro:
0
0
0
0
0
0
0
0
37
0
0
0
0
10
10
% P
% Gln:
0
19
0
0
0
0
10
0
0
0
10
0
19
0
0
% Q
% Arg:
0
73
10
10
10
0
10
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
10
19
10
0
0
0
28
0
0
% S
% Thr:
0
0
0
0
0
0
0
19
0
0
10
0
0
37
37
% T
% Val:
19
0
0
0
37
64
10
0
0
0
46
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _