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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMP1
All Species:
12.12
Human Site:
Y95
Identified Species:
26.67
UniProt:
P01033
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01033
NP_003245.1
207
23171
Y95
A
M
E
S
V
C
G
Y
F
H
R
S
H
N
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q95KL9
207
23229
Y95
A
M
E
S
V
C
G
Y
F
H
R
S
H
N
R
Dog
Lupus familis
XP_538410
211
24134
L93
A
S
E
S
L
C
G
L
K
L
E
V
N
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P12032
205
22610
Y96
V
M
E
S
L
C
G
Y
A
H
K
S
Q
N
R
Rat
Rattus norvegicus
P30120
217
23775
Y95
A
M
E
S
L
C
G
Y
V
H
K
S
Q
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505385
182
20306
K73
Y
E
H
K
S
L
N
K
S
T
E
Y
L
I
A
Chicken
Gallus gallus
O42146
220
24294
Q100
P
S
T
E
V
C
G
Q
P
L
D
T
G
G
K
Frog
Xenopus laevis
O73746
214
24437
E99
S
L
C
G
V
K
L
E
V
N
K
Y
Q
Y
L
Zebra Danio
Brachydanio rerio
NP_878294
220
24449
V99
P
S
S
A
V
C
G
V
T
N
L
D
T
N
G
Tiger Blowfish
Takifugu rubipres
NP_001033040
220
24546
V100
P
V
S
A
V
C
G
V
T
L
D
A
S
G
K
Fruit Fly
Dros. melanogaster
Q9VH14
210
23961
I98
Q
D
D
A
M
C
G
I
N
L
D
L
G
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
39.3
N.A.
72.4
68.6
N.A.
40.5
39
36.9
32.7
35
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.5
57.3
N.A.
85
80.6
N.A.
59.4
53.6
55.1
52.7
55
45.7
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
33.3
N.A.
66.6
73.3
N.A.
0
20
6.6
26.6
20
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
46.6
N.A.
80
86.6
N.A.
0
33.3
33.3
40
46.6
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
28
0
0
0
0
10
0
0
10
0
0
10
% A
% Cys:
0
0
10
0
0
82
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
28
10
0
0
0
% D
% Glu:
0
10
46
10
0
0
0
10
0
0
19
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
82
0
0
0
0
0
19
19
10
% G
% His:
0
0
10
0
0
0
0
0
0
37
0
0
19
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
10
0
10
0
10
10
0
28
0
0
19
19
% K
% Leu:
0
10
0
0
28
10
10
10
0
37
10
10
10
0
10
% L
% Met:
0
37
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
10
19
0
0
10
46
0
% N
% Pro:
28
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
28
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
37
% R
% Ser:
10
28
19
46
10
0
0
0
10
0
0
37
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
19
10
0
10
10
0
0
% T
% Val:
10
10
0
0
55
0
0
19
19
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
37
0
0
0
19
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _