Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CST3 All Species: 13.94
Human Site: S28 Identified Species: 34.07
UniProt: P01034 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01034 NP_000090.1 146 15799 S28 V S P A A G S S P G K P P R L
Chimpanzee Pan troglodytes XP_514555 141 16331 P23 A V A L A W S P Q E E D R I I
Rhesus Macaque Macaca mulatta O19092 146 15839 S28 V S P A A G A S P G K P P R L
Dog Lupus familis XP_542857 142 16269 N25 L V A S T D L N K N K A K V L
Cat Felis silvestris
Mouse Mus musculus P21460 140 15512 T22 L A V A W A A T P K Q G P R M
Rat Rattus norvegicus P14841 140 15418 T22 L A V A W A G T S R P P P R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518631 78 8921
Chicken Gallus gallus P01038 139 15268 G23 M L V G A V L G S E D R S R L
Frog Xenopus laevis NP_001089082 133 14474 S17 L V V A A G A S A S R G G M L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P31726 135 14908 S23 L L A L A A V S S T R S T Q K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.8 97.2 32.1 N.A. 69.8 71.2 N.A. 29.4 43.1 36.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.5 98.6 50.6 N.A. 80.8 82.8 N.A. 40.4 65 54.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 93.3 13.3 N.A. 26.6 33.3 N.A. 0 20 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 33.3 N.A. 66.6 53.3 N.A. 0 26.6 53.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 26 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 30 50 60 30 30 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 20 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 30 10 10 0 20 0 20 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 0 10 10 30 0 10 0 10 % K
% Leu: 50 20 0 20 0 0 20 0 0 0 0 0 0 0 60 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 20 0 0 0 0 10 30 0 10 30 40 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 20 10 10 50 0 % R
% Ser: 0 20 0 10 0 0 20 40 30 10 0 10 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 20 0 10 0 0 10 0 0 % T
% Val: 20 30 40 0 0 10 10 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 20 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _