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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CST3
All Species:
13.94
Human Site:
S28
Identified Species:
34.07
UniProt:
P01034
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01034
NP_000090.1
146
15799
S28
V
S
P
A
A
G
S
S
P
G
K
P
P
R
L
Chimpanzee
Pan troglodytes
XP_514555
141
16331
P23
A
V
A
L
A
W
S
P
Q
E
E
D
R
I
I
Rhesus Macaque
Macaca mulatta
O19092
146
15839
S28
V
S
P
A
A
G
A
S
P
G
K
P
P
R
L
Dog
Lupus familis
XP_542857
142
16269
N25
L
V
A
S
T
D
L
N
K
N
K
A
K
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P21460
140
15512
T22
L
A
V
A
W
A
A
T
P
K
Q
G
P
R
M
Rat
Rattus norvegicus
P14841
140
15418
T22
L
A
V
A
W
A
G
T
S
R
P
P
P
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518631
78
8921
Chicken
Gallus gallus
P01038
139
15268
G23
M
L
V
G
A
V
L
G
S
E
D
R
S
R
L
Frog
Xenopus laevis
NP_001089082
133
14474
S17
L
V
V
A
A
G
A
S
A
S
R
G
G
M
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P31726
135
14908
S23
L
L
A
L
A
A
V
S
S
T
R
S
T
Q
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.8
97.2
32.1
N.A.
69.8
71.2
N.A.
29.4
43.1
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.5
98.6
50.6
N.A.
80.8
82.8
N.A.
40.4
65
54.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
13.3
N.A.
26.6
33.3
N.A.
0
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
33.3
N.A.
66.6
53.3
N.A.
0
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
26
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
30
50
60
30
30
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
30
10
10
0
20
0
20
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
30
0
10
0
10
% K
% Leu:
50
20
0
20
0
0
20
0
0
0
0
0
0
0
60
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
20
0
0
0
0
10
30
0
10
30
40
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
20
10
10
50
0
% R
% Ser:
0
20
0
10
0
0
20
40
30
10
0
10
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
20
0
10
0
0
10
0
0
% T
% Val:
20
30
40
0
0
10
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _