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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CST3 All Species: 21.82
Human Site: Y68 Identified Species: 53.33
UniProt: P01034 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01034 NP_000090.1 146 15799 Y68 N K A S N D M Y H S R A L Q V
Chimpanzee Pan troglodytes XP_514555 141 16331 Y63 N K A T E D E Y Y R R P L R V
Rhesus Macaque Macaca mulatta O19092 146 15839 Y68 N K A S N D M Y H S R A L Q V
Dog Lupus familis XP_542857 142 16269 Y64 N K E S E D K Y L F Q V V K T
Cat Felis silvestris
Mouse Mus musculus P21460 140 15512 Y62 N K G S N D A Y H S R A I Q V
Rat Rattus norvegicus P14841 140 15418 Y62 N K G S N D A Y H S R A I Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518631 78 8921 E10 Y A V Q L L Q E E K E I V A G
Chicken Gallus gallus P01038 139 15268 Y63 N R A S N D K Y S S R V V R V
Frog Xenopus laevis NP_001089082 133 14474 F57 N K Q S N D M F L N T I T K V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P31726 135 14908 R61 L Q L Q E L A R F A V N E H N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.8 97.2 32.1 N.A. 69.8 71.2 N.A. 29.4 43.1 36.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.5 98.6 50.6 N.A. 80.8 82.8 N.A. 40.4 65 54.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 33.3 N.A. 80 80 N.A. 0 60 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 73.3 100 53.3 N.A. 86.6 86.6 N.A. 6.6 80 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 26 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 40 0 0 0 30 0 0 10 0 40 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 30 0 10 10 10 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 10 0 0 0 0 0 % F
% Gly: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 40 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 20 20 0 0 % I
% Lys: 0 70 0 0 0 0 20 0 0 10 0 0 0 20 0 % K
% Leu: 10 0 10 0 10 20 0 0 20 0 0 0 30 0 0 % L
% Met: 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 % M
% Asn: 80 0 0 0 60 0 0 0 0 10 0 10 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 10 10 20 0 0 10 0 0 0 10 0 0 40 0 % Q
% Arg: 0 10 0 0 0 0 0 10 0 10 60 0 0 20 0 % R
% Ser: 0 0 0 70 0 0 0 0 10 50 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 10 % T
% Val: 0 0 10 0 0 0 0 0 0 0 10 20 30 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 70 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _